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Stockholders' Equity (Tables)
3 Months Ended
Mar. 31, 2023
Stockholders' Equity [Abstract]  
Schedule of stock-based compensation
   For the Three Months Ended
March 31,
 
   2023   2022 
Research and development  $11,772   $28,808 
General and administrative   325,829    427,615 
Total  $337,601   $456,423 

 

Schedule of stock options outstanding and exercisable
           Weighted Average     
   Stock Options   Exercise Price   Fair
Value
   Contractual
Life
   Aggregate
Intrinsic
 
   Outstanding   Exercisable   Outstanding   Exercisable   Vested   (Years)   Value 
Balance – December 31, 2022   317,857    194,853   $44.53   $38.53   $38.53    6.99   $      - 
Granted   -    -    -    -    -    -    - 
Exercised   -    -    -    -    -    -    - 
Cancelled   (64,863)   -    -    -    -    -    - 
Balance – March 31, 2023   252,994    195,192   $46.03   $40.21   $40.21    6.63   $- 

 

Schedule of stock option activity
Grant Price   Weighted Average
Exercise
   Total   Number   Weighted Average
From   To   Price   Outstanding   Exercisable   Remaining Contractual Term
$6.00   $60.60   $35.90    220,259    146,796   6.58 years
$63.00   $138.00   $83.16    21,301    36,962   4.07 years
$159.00   $181.20   $172.14    11,434    11,434   4.84 years
           Totals    252,994    195,192    

 

Schedule of warrant activity
           Weighted Average     
   Warrants   Exercise Price   Fair
Value
   Contractual
Life
   Aggregate
Intrinsic
 
   Outstanding   Exercisable   Outstanding   Exercisable   Vested   (Years)   Value 
Balance – December 31, 2022   1,178,169    1,178,169   $30.67   $30.67   $17.83    3.41   $         - 
Granted   -    -    -    -    -    -    - 
Exercised   -    -    -    -    -    -    - 
Cancelled   (854)   -    -    -    -    -    - 
Balance – March 31, 2023   1,177,315    1,177,315   $30.66   $30.66   $17.79    3.16   $-