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Acquisition - Additional Information (Details) - Rodin Therapeutics, Inc. - USD ($)
12 Months Ended
Nov. 18, 2019
Dec. 31, 2021
Business Acquisition [Line Items]    
Business acquisition, date of acquisition agreement Nov. 18, 2019  
Business acquisition, date of acquisition completed Nov. 25, 2019  
Upfront cash payment $ 98,100,000  
Research and development expense 86,594,000  
Contingent consideration payments   $ 25,000,000.0
Milestones future payments   $ 825,000,000.0
IPR&D    
Business Acquisition [Line Items]    
Payment attributed to acquire IPR&D 98,100,000  
Maximum    
Business Acquisition [Line Items]    
Upfront cash future payments 850,000,000.0  
Achievement of Specified Clinical Milestones | Maximum    
Business Acquisition [Line Items]    
Upfront cash future payments 225,000,000.0  
Achievement of Regulatory Milestones | Maximum    
Business Acquisition [Line Items]    
Upfront cash future payments 300,000,000.0  
Attainment of Sales Thresholds | Maximum    
Business Acquisition [Line Items]    
Upfront cash future payments $ 325,000,000.0