LICENSE, COLLABORATION AND OTHER REVENUE - Japan Tobacco, Inc. and Torii Pharmaceutical Co., Ltd. Sublicense Agreement (Details) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2023 USD ($)	Sep. 30, 2022 USD ($)	Sep. 30, 2023 USD ($) performanceObligation	Sep. 30, 2022 USD ($)
License, collaboration and other revenue:
Recognized revenue	$ 42,046	$ 48,714	$ 138,427	$ 236,702
JT and Torii Sublicense Agreement | Sublicense Agreement
License, collaboration and other revenue:
Number of performance obligations | performanceObligation			2
Recognized revenue	$ 1,400	$ 1,200	$ 4,000	$ 3,900