UNAUDITED CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2023	Sep. 30, 2022	Sep. 30, 2023	Sep. 30, 2022
Revenues
Total revenues	$ 42,046	$ 48,714	$ 138,427	$ 236,702
Cost of goods sold
Product	8,998	29,270	28,452	61,965
Amortization of intangible asset	9,011	9,011	27,032	27,032
Total cost of goods sold	18,009	38,281	55,484	88,997
Operating expenses:
Research and development	13,330	28,028	53,214	97,888
Selling, general and administrative	22,710	31,887	74,797	108,693
License expense	864	743	2,381	2,323
Restructuring	169	180	181	14,711
Total operating expenses	37,073	60,838	130,573	223,615
Loss from operations	(13,036)	(50,405)	(47,630)	(75,910)
Other income (expense)
Interest expense	(1,410)	(3,952)	(4,614)	(14,051)
Other (expense) income	(43)	1,167	229	2,712
Loss on extinguishment of debt	0	(906)	0	(906)
Loss on termination of lease	0	0	(524)	0
Net (loss) income, basic	(14,489)	(54,096)	(52,539)	(88,155)
Net (loss) income, diluted	(14,489)	(54,096)	(52,539)	(88,155)
Comprehensive loss	$ (14,489)	$ (54,096)	$ (52,539)	$ (88,155)
Net loss per share:
Basic (in dollars per share)	$ (0.08)	$ (0.29)	$ (0.28)	$ (0.48)
Diluted (in dollars per share)	$ (0.08)	$ (0.29)	$ (0.28)	$ (0.48)
Weighted average common shares outstanding:
Basic (in shares)	188,306,350	183,882,446	186,643,878	182,375,443
Diluted (in shares)	188,306,350	183,882,446	186,643,878	182,375,443
Product revenue, net
Revenues
Total revenues	$ 40,118	$ 41,989	$ 117,068	$ 126,670
License, collaboration and other revenue
Revenues
Total revenues	$ 1,928	$ 6,725	$ 21,359	$ 110,032