UNAUDITED CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE INCOME (LOSS) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2023	Jun. 30, 2022	Jun. 30, 2023	Jun. 30, 2022
Revenues
Total revenues	$ 56,376	$ 126,365	$ 96,381	$ 187,988
Cost of goods sold
Product	8,273	9,589	19,452	32,694
Amortization of intangible asset	9,011	9,011	18,021	18,021
Total cost of goods sold	17,284	18,600	37,473	50,715
Operating expenses:
Research and development	20,197	26,027	39,883	69,860
Selling, general and administrative	27,036	32,240	52,090	76,806
License expense	949	892	1,517	1,580
Restructuring	(94)	14,531	12	14,531
Total operating expenses	48,088	73,690	93,502	162,777
Operating (loss) income	(8,996)	34,075	(34,594)	(25,504)
Other income (expense)
Interest expense	(1,642)	(5,037)	(3,204)	(10,099)
Other (expense) income	(10)	411	272	1,545
Net (loss) income, basic	(11,172)	29,449	(38,050)	(34,058)
Net (loss) income, diluted	(11,172)	29,449	(38,050)	(34,058)
Comprehensive (loss) income	(11,172)	29,449	(38,050)	(34,058)
Loss on lease termination	$ (524)	$ 0	$ (524)	$ 0
Net (loss) income per share:
Basic (in dollars per share)	$ (0.06)	$ 0.16	$ (0.20)	$ (0.19)
Diluted (in dollars per share)	$ (0.06)	$ 0.15	$ (0.20)	$ (0.19)
Weighted Average Number Of Shares Outstanding, Basic And Diluted [Abstract]
Basic (in shares)	186,817,431	183,597,766	185,798,865	181,609,452
Diluted (in shares)	186,817,431	190,375,317	185,798,865	181,609,452
Product revenue, net
Revenues
Total revenues	$ 42,244	$ 43,309	$ 76,950	$ 84,681
License, collaboration and other revenue
Revenues
Total revenues	$ 14,132	$ 83,056	$ 19,431	$ 103,307