Intangible Assets and Goodwill - Narrative (Details)	3 Months Ended				6 Months Ended	12 Months Ended
	Dec. 31, 2022	Mar. 31, 2021	Dec. 31, 2020	Jun. 30, 2020 USD ($)	Sep. 30, 2020	Dec. 31, 2022 USD ($) segment	Dec. 31, 2021 USD ($)	Dec. 31, 2020 USD ($)
Finite-Lived Intangible Assets [Line Items]
Intangible assets, estimated useful life	6 years
Amortization expense						$ 36,043,000	$ 36,043,000	$ 31,515,000
Impairment of intangible asset				$ 115,500,000		$ 0	0	115,527,000
Number of operating segments | segment						1
Goodwill impairment							0	0
Measurement Input, Discount Rate | Valuation Technique, Discounted Cash Flow
Finite-Lived Intangible Assets [Line Items]
Intangible asset, fair value, measurement input	0.095					0.095
Developed product rights for Auryxia
Finite-Lived Intangible Assets [Line Items]
Intangible assets, estimated useful life		9 years	6 years		7 years	6 years
Amortization expense						$ 36,000,000	$ 36,000,000	$ 31,500,000