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Debt - Additional Information (Details)
3 Months Ended 9 Months Ended
Jul. 15, 2022
USD ($)
Dec. 10, 2020
USD ($)
Nov. 11, 2019
USD ($)
tranche
Sep. 30, 2022
USD ($)
Sep. 30, 2021
USD ($)
Sep. 30, 2022
USD ($)
Sep. 30, 2021
USD ($)
Dec. 31, 2021
USD ($)
Nov. 25, 2019
USD ($)
Line of Credit Facility [Line Items]                  
Term loan, net of facility fees, lender expenses and issuance costs       $ 65,947,000   $ 65,947,000      
Loss on extinguishment of debt       906,000 $ 0 906,000 $ 0    
Derivative liability       760,000   760,000   $ 1,820,000  
Collateral Agent, Pharmakon                  
Line of Credit Facility [Line Items]                  
Derivative liability       800,000   800,000   $ 1,800,000  
Term Loan | Collateral Agent, Pharmakon | Tranche A and B                  
Line of Credit Facility [Line Items]                  
Payment for debt prepayment $ 25,000,000                
Payment for debt prepayment premium, including accrued and unpaid interest 500,000                
Loss on extinguishment of debt       900,000   900,000      
Term Loan | Collateral Agent, Pharmakon | Tranche A                  
Line of Credit Facility [Line Items]                  
Payment for debt prepayment 5,000,000                
Term Loan | Collateral Agent, Pharmakon | Tranche B                  
Line of Credit Facility [Line Items]                  
Payment for debt prepayment $ 20,000,000                
Biopharma Credit Investments V (Master) LP | Keryx | Term Loan | Collateral Agent, Pharmakon                  
Line of Credit Facility [Line Items]                  
Line of credit, maximum borrowing capacity     $ 100,000,000            
Line of credit, maximum borrowing capacity, number of available tranches | tranche     2            
Term loan, maturity term     5 years            
Term loan, principal payment           8,000,000      
Term loan, maturity term, potential reduction (up to)     1 year            
Term loan, amortization period, potential reduction (up to)     1 year            
Facility fee percentage on principal amount     2.00%            
Facility fee paid, amount     $ 2,000,000            
Prepayment premium percentage on principal if prepaid prior to third anniversary of funding     2.00%            
Prepayment premium percentage on principal if prepaid prior to fourth anniversary and after third anniversary of funding     1.00%            
Prepayment premium percentage on principal if prepaid after fourth anniversary of funding     0.50%            
Interest expense       $ 2,100,000 $ 2,700,000 $ 7,500,000 $ 8,100,000    
Biopharma Credit Investments V (Master) LP | Keryx | Term Loan | Collateral Agent, Pharmakon | Debt Instrument, Quarterly Periodic Payment, Period One                  
Line of Credit Facility [Line Items]                  
Term loan, first quarterly principal payment due in     33 months            
Biopharma Credit Investments V (Master) LP | Keryx | Term Loan | Collateral Agent, Pharmakon | Debt Instrument, Quarterly Periodic Payment, Period Two                  
Line of Credit Facility [Line Items]                  
Term loan, first quarterly principal payment due in     48 months            
Biopharma Credit Investments V (Master) LP | Keryx | Term Loan | Collateral Agent, Pharmakon | Three-month LIBOR                  
Line of Credit Facility [Line Items]                  
Basis spread on floating interest rate     7.50%            
Biopharma Credit Investments V (Master) LP | Keryx | Term Loan | Collateral Agent, Pharmakon | LIBOR                  
Line of Credit Facility [Line Items]                  
Debt instrument, floor rate     2.00%            
Debt instrument, cap rate     3.35%            
Biopharma Credit Investments V (Master) LP | Keryx | Term Loan | Collateral Agent, Pharmakon | Tranche A                  
Line of Credit Facility [Line Items]                  
Line of credit, maximum borrowing capacity     $ 80,000,000            
Term loan, net of facility fees, lender expenses and issuance costs                 $ 77,300,000
Biopharma Credit Investments V (Master) LP | Keryx | Term Loan | Collateral Agent, Pharmakon | Tranche B                  
Line of Credit Facility [Line Items]                  
Line of credit, maximum borrowing capacity     $ 20,000,000            
BPCR Limited Partnership | Keryx | Term Loan | Collateral Agent, Pharmakon | Tranche B                  
Line of Credit Facility [Line Items]                  
Proceeds from line of credit   $ 20,000,000