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Inventory - Additional Information (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2022
Mar. 31, 2022
Sep. 30, 2021
Sep. 30, 2022
Sep. 30, 2021
Business Acquisition [Line Items]          
Inventory amounts written down $ 2,600   $ 1,700 $ 10,002 $ 7,126
Inventory adjustments to previous reserves $ 5,800 $ 3,200   14,800  
Keryx Biopharmaceuticals, Inc.          
Business Acquisition [Line Items]          
Inventory step-up charges       $ 0 $ 8,700