Condensed Consolidated Statements of Stockholders' Equity - USD ($) $ in Thousands	Total	Common Stock	Additional Paid-In Capital	Unrealized Gain/(Loss)	Accumulated Deficit
Beginning balance (in shares) at Dec. 31, 2020		148,074,085
Beginning balance at Dec. 31, 2020	$ 247,618	$ 1	$ 1,425,115	$ 13	$ (1,177,511)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of common stock, net of issuance costs (in shares)		9,228,017
Issuance of common stock, net of    issuance costs	29,498	$ 1	29,497
Proceeds from sale of stock under employee stock purchase plan (in shares)		154,276
Proceeds from sale of stock under    employee stock purchase plan	367		367
Stock-based compensation expense	5,992		5,992
Restricted stock unit vesting (in shares)		1,063,711
Unrealized loss	(4)			(4)
Net income (loss)	(69,580)				(69,580)
Ending balance (in shares) at Mar. 31, 2021		158,520,089
Ending balance at Mar. 31, 2021	213,891	$ 2	1,460,971	9	(1,247,091)
Beginning balance (in shares) at Dec. 31, 2020		148,074,085
Beginning balance at Dec. 31, 2020	247,618	$ 1	1,425,115	13	(1,177,511)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Unrealized loss	(7)
Net income (loss)	(212,162)
Ending balance (in shares) at Sep. 30, 2021		174,551,989
Ending balance at Sep. 30, 2021	137,150	$ 2	1,526,815	6	(1,389,673)
Beginning balance (in shares) at Mar. 31, 2021		158,520,089
Beginning balance at Mar. 31, 2021	213,891	$ 2	1,460,971	9	(1,247,091)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of common stock, net of issuance costs (in shares)		10,446,160
Issuance of common stock, net of    issuance costs	37,266		37,266
Stock-based compensation expense	6,515		6,515
Restricted stock unit vesting (in shares)		685,174
Unrealized loss	(3)			(3)
Net income (loss)	(83,038)				(83,038)
Ending balance (in shares) at Jun. 30, 2021		169,651,423
Ending balance at Jun. 30, 2021	174,631	$ 2	1,504,752	6	(1,330,129)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of common stock, net of issuance costs (in shares)		4,730,466
Issuance of common stock, net of    issuance costs	16,092	$ 0	16,092
Proceeds from sale of stock under employee stock purchase plan (in shares)		152,917
Proceeds from sale of stock under    employee stock purchase plan	379		379
Stock-based compensation expense	5,592		5,592
Restricted stock unit vesting (in shares)		17,183
Unrealized loss	0
Net income (loss)	(59,544)				(59,544)
Ending balance (in shares) at Sep. 30, 2021		174,551,989
Ending balance at Sep. 30, 2021	$ 137,150	$ 2	1,526,815	6	(1,389,673)
Beginning balance (in shares) at Dec. 31, 2021	177,000,963	177,000,963
Beginning balance at Dec. 31, 2021	$ 76,456	$ 1	1,536,800	6	(1,460,351)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of common stock, net of issuance costs (in shares)		4,404,600
Issuance of common stock, net of    issuance costs	7,178	$ 1	7,177
Proceeds from sale of stock under employee stock purchase plan (in shares)		191,146
Proceeds from sale of stock under    employee stock purchase plan	367		367
Stock-based compensation expense	4,536		4,536
Restricted stock unit vesting (in shares)		1,789,326
Net income (loss)	(62,421)				(62,421)
Ending balance (in shares) at Mar. 31, 2022		183,386,035
Ending balance at Mar. 31, 2022	$ 26,116	$ 2	1,548,880	6	(1,522,772)
Beginning balance (in shares) at Dec. 31, 2021	177,000,963	177,000,963
Beginning balance at Dec. 31, 2021	$ 76,456	$ 1	1,536,800	6	(1,460,351)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Unrealized loss	0
Net income (loss)	$ (85,010)
Ending balance (in shares) at Sep. 30, 2022	183,951,583	183,951,583
Ending balance at Sep. 30, 2022	$ 13,853	$ 2	1,559,206	6	(1,545,361)
Beginning balance (in shares) at Mar. 31, 2022		183,386,035
Beginning balance at Mar. 31, 2022	26,116	$ 2	1,548,880	6	(1,522,772)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Stock-based compensation expense	6,841		6,841
Exercise of options (in shares)		142,440
Exercise of options	67		67
Restricted stock unit vesting (in shares)		176,179
Net income (loss)	29,276				29,276
Ending balance (in shares) at Jun. 30, 2022		183,704,654
Ending balance at Jun. 30, 2022	62,300	$ 2	1,555,788	6	(1,493,496)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Proceeds from sale of stock under employee stock purchase plan (in shares)		144,000
Proceeds from sale of stock under    employee stock purchase plan	43		43
Stock-based compensation expense	3,375		3,375
Restricted stock unit vesting (in shares)		102,929
Unrealized loss	0
Net income (loss)	$ (51,865)				(51,865)
Ending balance (in shares) at Sep. 30, 2022	183,951,583	183,951,583
Ending balance at Sep. 30, 2022	$ 13,853	$ 2	$ 1,559,206	$ 6	$ (1,545,361)