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License, Collaboration and Other Significant Agreements - License Agreement with Panion & BF Biotech, Inc. (Details) - USD ($)
$ in Millions
3 Months Ended 9 Months Ended
Sep. 30, 2022
Sep. 30, 2021
Sep. 30, 2022
Sep. 30, 2021
JT and Torii | Panion & BF Biotech, Incorporation | License Agreement        
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]        
Royalty payments $ 2.9 $ 3.0 $ 9.5 $ 8.3