Product Revenue and Reserves for Variable Consideration - Product Revenue Allowance and Reserve Categories (Details) - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2022	Sep. 30, 2021
SEC Schedule, 12-09, Movement in Valuation Allowances and Reserves [Roll Forward]
Beginning balance	$ 28,378	$ 41,363
Current provisions related to sales in current year	76,606	119,209
Adjustments related to prior year sales	(215)	(1,591)
Credits/payments made	(77,474)	(113,090)
Ending balance	27,295	45,891
Chargebacks and Discounts
SEC Schedule, 12-09, Movement in Valuation Allowances and Reserves [Roll Forward]
Beginning balance	1,278	802
Current provisions related to sales in current year	8,592	8,911
Adjustments related to prior year sales	(248)	(1)
Credits/payments made	(8,194)	(8,593)
Ending balance	1,428	1,119
Rebates, Fees and other Deductions
SEC Schedule, 12-09, Movement in Valuation Allowances and Reserves [Roll Forward]
Beginning balance	26,625	39,912
Current provisions related to sales in current year	64,322	105,432
Adjustments related to prior year sales	33	(1,590)
Credits/payments made	(65,611)	(99,518)
Ending balance	25,369	44,236
Returns
SEC Schedule, 12-09, Movement in Valuation Allowances and Reserves [Roll Forward]
Beginning balance	475	649
Current provisions related to sales in current year	3,692	4,866
Adjustments related to prior year sales	0	0
Credits/payments made	(3,669)	(4,979)
Ending balance	$ 498	$ 536