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Intangible Assets and Goodwill - Narrative (Details)
3 Months Ended 6 Months Ended 12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Jun. 30, 2020
USD ($)
Mar. 31, 2020
Sep. 30, 2020
Dec. 31, 2021
USD ($)
segment
Dec. 31, 2020
USD ($)
Dec. 31, 2019
USD ($)
Finite-Lived Intangible Assets [Line Items]                
Intangible assets, estimated useful life 6 years              
Amortization expense           $ 36,043,000 $ 31,515,000 $ 36,401,000
Impairment of intangible asset     $ 115,500,000     $ 0 115,527,000 0
Number of operating segments | segment           1    
Goodwill impairment           $ 0 0 0
Measurement Input, Discount Rate | Valuation Technique, Discounted Cash Flow                
Finite-Lived Intangible Assets [Line Items]                
Intangible asset, fair value, measurement input 0.095         0.095    
Developed product rights for Auryxia                
Finite-Lived Intangible Assets [Line Items]                
Intangible assets, estimated useful life   6 years   9 years 7 years 6 years    
Amortization expense           $ 36,000,000 $ 31,500,000 $ 36,400,000