Inventory - Additional Information (Details) - USD ($) $ in Thousands	3 Months Ended	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Inventory [Line Items]
Write-down of inventory		$ 15,618	$ 20,072	$ 7,112
Receipts related to inventory	$ 12,500
Keryx Biopharmaceuticals, Inc.
Inventory [Line Items]
Inventory step-up charges		$ 8,700	$ 11,400	$ 17,100