Liability Related to Sale of Future Royalties - Narrative (Details) - USD ($) $ in Thousands		12 Months Ended
	Feb. 25, 2021	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Other Liabilities Disclosure [Abstract]
Maximum annual royalty payout capacity	$ 13,000
Maximum aggregate royalty payout capacity	$ 150,000
Percentage of royalty payment to be received once maximum annual royalty payout has been paid	85.00%
Proceeds from sale of future royalties, net	$ 44,800	$ 44,783	$ 0	$ 0
Eligible proceeds to be received, contingent on annual sales milestones	5,000
Liability related to sale of future royalties, net	$ 44,800	$ 53,079	$ 0
Annual effective interest rate		18.30%