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Product Revenue, Net (Tables)
12 Months Ended
Dec. 31, 2021
Revenue from Contract with Customer [Abstract]  
Summary of Product Revenue Allowance and Reserve Categories The following table summarizes activity in each of the product revenue allowance and reserve categories for the years ended December 31, 2019, 2020, and 2021 (in thousands):
 Chargebacks
and
Discounts
Rebates, Fees
and other
Deductions
ReturnsTotal
Balance at December 31, 2018$516 $22,861 $360 $23,737 
Provisions related to sales in current year7,822 110,866 2,008 120,696 
Adjustments related to prior year sales— 1,149 — $1,149 
Credits/payments made(7,600)(104,324)(2,115)$(114,039)
Balance at December 31, 2019738 30,552 253 31,543 
Current provisions related to sales in current year10,559 149,472 7,238 167,269 
Adjustments related to prior year sales— 377 — 377 
Credits/payments made(10,495)(140,489)(6,842)(157,826)
Balance at December 31, 2020$802 $39,912 $649 $41,363 
Current provisions related to sales in current year11,759 133,297 5,852 150,908 
Adjustments related to prior year sales(1)(1,790)— (1,791)
Credits/payments made(11,282)(144,794)(6,026)(162,102)
Balance at December 31, 2021$1,278 $26,625 $475 $28,378