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Inventory - Additional Information (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2021
Sep. 30, 2020
Sep. 30, 2021
Sep. 30, 2020
Business Acquisition [Line Items]        
Inventory amounts written down $ 1,700 $ 8,500 $ 7,126 $ 18,608
Keryx Biopharmaceuticals, Inc.        
Business Acquisition [Line Items]        
Inventory step-up charges $ 0 $ 1,400 $ 8,700 $ 7,400