Product Revenue and Reserves for Variable Consideration - Additional Information (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2021	Sep. 30, 2020	Sep. 30, 2021	Sep. 30, 2020	Dec. 31, 2020
Disaggregation of Revenue [Line Items]
Total revenues	$ 48,756	$ 59,988	$ 153,973	$ 238,608
Product revenue, net
Disaggregation of Revenue [Line Items]
Total revenues	36,753	$ 34,392	100,120	$ 94,297
Accounts receivable, net	$ 22,200		$ 22,200		$ 21,900