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Product Revenue and Reserves for Variable Consideration - Additional Information (Details) - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2021
Mar. 31, 2020
Dec. 31, 2020
Disaggregation of Revenue [Line Items]      
Total revenues $ 52,304 $ 88,478  
Product revenue, net      
Disaggregation of Revenue [Line Items]      
Total revenues 30,408 $ 29,209  
Accounts receivable, net $ 28,300   $ 21,900