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License, Collaboration and Other Significant Agreements - Mitsubishi Tanabe Pharma Corporation Collaboration Agreement (Details)		1 Months Ended	3 Months Ended		9 Months Ended
	Dec. 11, 2015 USD ($)	Nov. 05, 2020 USD ($)	Sep. 30, 2020 USD ($)	Sep. 30, 2019 USD ($)	Sep. 30, 2020 USD ($) performanceObligation	Sep. 30, 2019 USD ($)	Dec. 31, 2019 USD ($)	Dec. 31, 2018 USD ($)
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Recognized revenue			$ 59,988,000	$ 91,977,000	$ 238,608,000	$ 265,446,000
Revenue recognized			6,537,000	27,095,000	29,203,000	60,441,000
Deferred revenue			51,694,000		51,694,000
Deferred revenue, net of current portion			33,660,000		33,660,000		$ 33,120,000
Short-term deferred revenue			18,034,000		18,034,000		39,830,000
Accounts receivable
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Accounts receivable			2,761,000	4,204,000	2,761,000	4,204,000	$ 15,822,000	$ 1,587,000
Mitsubishi Tanabe Pharma Corporation
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Recognized revenue			400,000	0
Mitsubishi Tanabe Pharma Corporation \| Regulatory Milestone, Approval Of Vadadustat In Japan
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Recognized revenue					15,000,000.0
Mitsubishi Tanabe Pharma Corporation \| Regulatory Milestone Payments
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Milestone revenue					25,000,000.0
Mitsubishi Tanabe Pharma Corporation \| Mitsubishi Tanabe Pharma Corporation Collaboration Agreement, Global Phase 3 Program
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Proceeds from collaborators	$ 0
Mitsubishi Tanabe Pharma Corporation \| Development and Commercialize Collaboration Agreement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Milestone revenue					$ 10,000,000.0
Collaboration agreement, expiration period					10 years
Collaboration agreement, notice period for termination					12 months
Upfront cash payment received					$ 20,000,000.0
Additional milestone or royalty payments received					$ 0
Number of performance obligations \| performanceObligation					2
Mitsubishi Tanabe Pharma Corporation \| Development and Commercialize Collaboration Agreement \| Maximum
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Percentage of royalty payments on sales					20.00%
Mitsubishi Tanabe Pharma Corporation \| Development and Commercialize Collaboration Agreement \| Regulatory Milestone Payments
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Milestone revenue			15,000,000.0	$ 10,000,000.0	$ 25,000,000.0
Mitsubishi Tanabe Pharma Corporation \| Development and Commercialize Collaboration Agreement \| Regulatory Milestone Payments \| Maximum
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Upfront cash payment received					40,000,000.0
Mitsubishi Tanabe Pharma Corporation \| Development and Commercialize Collaboration Agreement \| Development Regulatory And Commercial Events Milestones Payment \| Maximum
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Potential milestone revenue					225,000,000.0
Mitsubishi Tanabe Pharma Corporation \| Development and Commercialize Collaboration Agreement \| Development Milestones
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Milestone revenue					10,000,000.0
Mitsubishi Tanabe Pharma Corporation \| Development and Commercialize Collaboration Agreement \| Commercial Milestone Payments \| Maximum
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Potential milestone revenue (up to)			175,000,000.0		175,000,000.0
Mitsubishi Tanabe Pharma Corporation \| Development and Commercialize Collaboration Agreement \| Upfront Payment
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Incurred clinical and commercial development cost					20,500,000
Mitsubishi Tanabe Pharma Corporation \| Development And Commercialize Research And License Agreement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Milestone revenue					10,000,000.0
Upfront cash payment received					20,000,000.0
Cost of research services					20,500,000
Accounts receivable			0		0
Deferred revenue			0		0
Mitsubishi Tanabe Pharma Corporation \| Development And Commercialize Research And License Agreement \| Accounts receivable
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Accounts receivable			400,000		400,000
Mitsubishi Tanabe Pharma Corporation \| Development And Commercialize Research And License Agreement \| Regulatory Milestone Payments
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Milestone revenue					10,000,000.0
Revenue recognized						$ 10,000,000.0
Mitsubishi Tanabe Pharma Corporation \| Mitsubishi Tanabe Pharma Corporation And Otsuka Pharmaceutical Company Limited
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Upfront cash payment received			10,400,000
Revenue recognized			500,000		4,500,000
Deferred revenue, net of current portion			0		0
Mitsubishi Tanabe Pharma Corporation \| Mitsubishi Tanabe Pharma Corporation And Otsuka Pharmaceutical Company Limited \| Subsequent Event
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Revenue recognized		$ 1,700,000
Mitsubishi Tanabe Pharma Corporation \| Mitsubishi Tanabe Pharma Corporation And Otsuka Pharmaceutical Company Limited \| Accounts receivable
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Accounts receivable			0		0
Mitsubishi Tanabe Pharma Corporation \| Mitsubishi Tanabe Pharma Corporation And Otsuka Pharmaceutical Company Limited \| Other Current Liabilities
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Short-term deferred revenue			5,900,000		5,900,000
Mitsubishi Tanabe Pharma Corporation \| Mitsubishi Tanabe Pharma Corporation And Otsuka Pharmaceutical Company Limited \| Other Current Liabilities \| Subsequent Event
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Short-term deferred revenue		4,200,000
Mitsubishi Tanabe Pharma Corporation \| Mitsubishi Tanabe Pharma Corporation Supply Agreement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Revenue recognized			$ 0		$ 0
Mitsubishi Tanabe Pharma Corporation \| Mitsubishi Tanabe Pharma Corporation Supply Agreement \| Subsequent Event
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Up-front payments invoiced		$ 18,900,000