Product Revenue and Reserves for Variable Consideration - Additional Information (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2020	Sep. 30, 2019	Sep. 30, 2020	Sep. 30, 2019	Dec. 31, 2019
Disaggregation of Revenue [Line Items]
Total revenues	$ 59,988	$ 91,977	$ 238,608	$ 265,446
Product revenue, net
Disaggregation of Revenue [Line Items]
Total revenues	34,392	$ 30,004	94,297	$ 82,204
Accounts receivable, net	$ 21,700		$ 21,700		$ 23,000