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Stockholders' Equity - Additional Information (Details)
3 Months Ended 6 Months Ended 12 Months Ended
May 19, 2020
USD ($)
$ / shares
shares
May 19, 2020
USD ($)
$ / shares
May 14, 2020
USD ($)
$ / shares
shares
Mar. 12, 2020
USD ($)
Feb. 28, 2020
shares
Nov. 12, 2019
USD ($)
Dec. 12, 2018
shares
Jun. 30, 2020
USD ($)
$ / shares
shares
Mar. 31, 2020
USD ($)
shares
Jun. 30, 2019
USD ($)
shares
Jun. 30, 2020
USD ($)
installment
$ / shares
shares
Jun. 30, 2019
USD ($)
shares
Dec. 31, 2019
USD ($)
$ / shares
shares
Jun. 04, 2020
shares
Mar. 31, 2019
shares
Dec. 31, 2018
shares
Feb. 28, 2014
shares
Class of Stock [Line Items]                                  
Common stock, shares authorized (in shares)               350,000,000     350,000,000   175,000,000 175,000,000      
Common stock, par value (in dollars per share) | $ / shares               $ 0.00001     $ 0.00001   $ 0.00001        
Common stock, shares issued (in shares)               143,129,409     143,129,409   121,674,568        
Common stock, shares outstanding (in shares)               143,129,409     143,129,409   121,674,568        
Preferred stock, shares authorized (in shares)               25,000,000     25,000,000   25,000,000        
Preferred stock, par value (in dollars per share) | $ / shares               $ 0.00001     $ 0.00001   $ 0.00001        
Preferred stock, shares issued (in shares)               0     0   0        
Preferred stock, shares outstanding (in shares)               0     0   0        
Proceeds from the issuance of common stock, net of issuance costs | $                     $ 198,883,000 $ 9,035,000          
Common stock, shares reserved for future issuance (in shares)               24,926,906     24,926,906   21,403,890        
Stock-based compensation expense | $               $ 6,864,000   $ 2,284,000 $ 11,780,000 4,378,000          
Follow-On Public Offering                                  
Class of Stock [Line Items]                                  
Number of shares sold in offering (in shares)     11,000,000                            
Offering price per share (in dollars per share) | $ / shares     $ 12.00                            
Aggregate net proceeds from offering | $   $ 142,400,000 $ 123,800,000                            
Over-Allotment Option                                  
Class of Stock [Line Items]                                  
Number of shares sold in offering (in shares) 1,650,000                                
Offering price per share (in dollars per share) | $ / shares $ 12.00 $ 12.00                              
Aggregate net proceeds from offering | $ $ 18,600,000                                
Inducement Award Program                                  
Class of Stock [Line Items]                                  
Number of shares granted (in shares)                     786,750            
Number of shares outstanding (in shares)               786,750     786,750            
Inducement Award Program | Employees                                  
Class of Stock [Line Items]                                  
Number of shares granted (in shares)                     786,750            
Stock options                                  
Class of Stock [Line Items]                                  
Number of shares issued (in shares)         1,714,800                        
Stock-based compensation description                     Options vest either 100% on the first anniversary of the grant date or in installments of (i) 25% at the one year anniversary and (ii) 12 equal quarterly installments beginning after the one year anniversary of the grant date, subject to the individual’s continuous service with the Company            
Options expiration after the date of grant                     10 years            
Stock-based compensation expense | $               $ 2,366,000   1,073,000 $ 3,983,000 $ 2,185,000          
Stock options | Share-based Compensation Award, Tranche, First Anniversary of Grant Date                                  
Class of Stock [Line Items]                                  
Vesting percentage                     100.00%            
Stock options | Share Based Compensation Award Tranche One                                  
Class of Stock [Line Items]                                  
Vesting periods                     1 year            
Vesting percentage                     25.00%            
Stock options | Share Based Compensation Award Tranche Two                                  
Class of Stock [Line Items]                                  
Number of equal quarterly installments | installment                     12            
Performance-Based Stock Options                                  
Class of Stock [Line Items]                                  
Number of shares granted (in shares)                     0 0          
Number of shares outstanding (in shares)               0     0   46,790        
Vesting percentage, Following achievement of performance condition             50.00%                    
Performance-Based Stock Options | Keryx Biopharmaceuticals, Inc. | Merger Agreement                                  
Class of Stock [Line Items]                                  
Number of shares granted (in shares)             233,954                    
Restricted stock units                                  
Class of Stock [Line Items]                                  
Stock-based compensation description                     Generally, RSUs granted by the Company vest in one of the following ways: (i) 100% of each RSU grant vests on either the first or the third anniversary of the grant date, (ii) one third of each RSU grant vests on the first, second and third anniversaries of the grant date, subject, in each case, to the individual’s continued service through the applicable vesting date, or (iii) 50% of each RSU grant vests on the first anniversary and 25% of each RSU grant vests in 6 months increment after the one year anniversary of the grant date.            
Stock-based compensation expense | $               $ 4,344,000   1,168,000 $ 7,486,000 $ 2,102,000          
Restricted stock units | Share-Based Payment Arrangement, Tranche One, First Anniversary After Grant Date, Subjected To Individual Continued Service                                  
Class of Stock [Line Items]                                  
Vesting percentage                     33.33%            
Restricted stock units | Share-Based Payment Arrangement, Tranche Two, Second Anniversary After Grant Date, Subjected To Individual Continued Service                                  
Class of Stock [Line Items]                                  
Vesting percentage                     33.33%            
Restricted stock units | Share-Based Payment Arrangement, Tranche Three, Third Anniversary After Grant Date, Subjected To Individual Continued Service                                  
Class of Stock [Line Items]                                  
Vesting percentage                     33.33%            
Service-Based Restricted Stock Units                                  
Class of Stock [Line Items]                                  
Number of shares granted (in shares)         2,268,000                        
Stock-based compensation expense | $               4,200,000   1,200,000 $ 7,200,000 2,100,000          
Service-Based Restricted Stock Units | Share-based Compensation Award, Tranche, First Or Third Anniversary of Grant Date                                  
Class of Stock [Line Items]                                  
Vesting percentage                     100.00%            
Service-Based Restricted Stock Units | Share Based Compensation Award Tranche One                                  
Class of Stock [Line Items]                                  
Vesting percentage                     50.00%            
Service-Based Restricted Stock Units | Share Based Compensation Award Tranche Two                                  
Class of Stock [Line Items]                                  
Vesting periods                     6 months            
Vesting percentage                     25.00%            
Performance Based Restricted Stock Unit                                  
Class of Stock [Line Items]                                  
Number of shares granted (in shares)         479,000                        
Stock-based compensation expense | $               $ 200,000   $ 0 $ 300,000 $ 0          
Common Stock                                  
Class of Stock [Line Items]                                  
Common stock, shares outstanding (in shares)               143,129,409 130,251,440 118,787,301 143,129,409 118,787,301 121,674,568   117,122,262 116,887,518  
Issuance of common stock, net of issuance costs (in shares)               12,650,000 7,973,967 1,384,520              
Maximum | Stock options                                  
Class of Stock [Line Items]                                  
Vesting periods                     48 months            
Maximum | Performance-Based Stock Options                                  
Class of Stock [Line Items]                                  
Potential share issuable percentage             100.00%                    
Vesting percentage, upon achievement of performance condition             50.00%                    
Maximum | Restricted stock units                                  
Class of Stock [Line Items]                                  
Vesting periods                     3 years            
Minimum | Stock options                                  
Class of Stock [Line Items]                                  
Vesting periods                     12 months            
Minimum | Performance-Based Stock Options                                  
Class of Stock [Line Items]                                  
Potential share issuable percentage             0.00%                    
Minimum | Restricted stock units                                  
Class of Stock [Line Items]                                  
Vesting periods                     1 year            
At The Market Equity Offering Program                                  
Class of Stock [Line Items]                                  
Common stock sales agreement amount | $               $ 0     $ 0            
At The Market Equity Offering Program | Common Stock                                  
Class of Stock [Line Items]                                  
Issuance of common stock, net of issuance costs (in shares)                 7,973,967       2,684,392        
Proceeds from the issuance of common stock, net of issuance costs | $                 $ 56,700,000       $ 16,800,000        
At The Market Equity Offering Program | Maximum                                  
Class of Stock [Line Items]                                  
Common stock sales agreement amount | $       $ 65,000,000.0   $ 75,000,000.0                      
2014 Plans                                  
Class of Stock [Line Items]                                  
Common stock, shares reserved for future issuance (in shares)                                 1,785,000
Incremental rate at which the shares reserved for issuance increase                     3.00%            
2014 Plans | Stock options | Employees                                  
Class of Stock [Line Items]                                  
Number of shares granted (in shares)                     1,714,800            
2014 Plans | Stock options | Director                                  
Class of Stock [Line Items]                                  
Number of shares granted (in shares)                     220,900            
2014 Plans | Restricted stock units | Employees                                  
Class of Stock [Line Items]                                  
Number of shares granted (in shares)                     2,367,500            
2014 Plans | Restricted stock units | Director                                  
Class of Stock [Line Items]                                  
Number of shares granted (in shares)                     95,900            
2014 Plans | Performance Based Restricted Stock Unit | Employees                                  
Class of Stock [Line Items]                                  
Number of shares granted (in shares)                     479,000            
2014 Employee Stock Purchase Plan                                  
Class of Stock [Line Items]                                  
Common stock, shares reserved for future issuance (in shares)               5,600,968     5,600,968            
Offering period                     6 months            
Purchase price at the end of offering period                     85.00%            
Number of shares issued (in shares)                     115,024            
Stock-based compensation expense | $               $ 154,000   $ 43,000 $ 311,000 $ 91,000