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Stockholders' Equity - Additional Information (Details)
3 Months Ended 12 Months Ended
Mar. 12, 2020
USD ($)
Feb. 28, 2020
shares
Nov. 12, 2019
USD ($)
Feb. 28, 2019
shares
Dec. 12, 2018
shares
Mar. 31, 2020
USD ($)
Installment
$ / shares
shares
Mar. 31, 2019
USD ($)
shares
Dec. 31, 2019
USD ($)
$ / shares
shares
Dec. 31, 2018
shares
Feb. 28, 2014
shares
Class of Stock [Line Items]                    
Common stock, shares authorized           175,000,000   175,000,000    
Common stock, par value | $ / shares           $ 0.00001   $ 0.00001    
Common stock, shares issued           130,251,440   121,674,568    
Common stock, shares outstanding           130,251,440   121,674,568    
Preferred stock, shares authorized           25,000,000   25,000,000    
Preferred stock, par value | $ / shares           $ 0.00001   $ 0.00001    
Preferred stock, shares issued           0   0    
Preferred stock, shares outstanding           0   0    
Proceeds from the issuance of common stock, net of issuance costs | $           $ 56,485,000        
Common stock, shares reserved for future issuance           24,958,932   21,403,890    
Stock-based compensation expense | $           $ 4,916,000 $ 2,094,000      
Inducement Award Program                    
Class of Stock [Line Items]                    
Granted, Shares           299,450        
Outstanding, Shares           299,450        
Inducement Award Program | Employees                    
Class of Stock [Line Items]                    
Granted, Shares           299,450        
Stock Options                    
Class of Stock [Line Items]                    
Shares issued       1,714,800            
Stock-based compensation description           Options vest either 100% on the first anniversary of the grant date or in installments of (i) 25% at the one year anniversary and (ii) 12 equal quarterly installments beginning after the one year anniversary of the grant date, subject to the individual’s continuous service with the Company        
Options expiration after the date of grant           10 years        
Stock-based compensation expense | $           $ 1,617,000 1,112,000      
Stock Options | Share-based Compensation Award, Tranche, First Anniversary of Grant Date                    
Class of Stock [Line Items]                    
Vesting percentage           100.00%        
Stock Options | Share Based Compensation Award Tranche One                    
Class of Stock [Line Items]                    
Vesting periods           1 year        
Vesting percentage           25.00%        
Stock Options | Share Based Compensation Award Tranche Two                    
Class of Stock [Line Items]                    
Number of equal quarterly installments | Installment           12        
Restricted Stock Units                    
Class of Stock [Line Items]                    
Granted, Shares   2,268,000                
Stock-based compensation description           Generally, RSUs granted by the Company vest in one of the following ways: (i) 100% of each RSU grant vests on either the first or the third anniversary of the grant date, (ii) one third of each RSU grant vests on the first, second and third anniversaries of the grant date, subject, in each case, to the individual’s continued service through the applicable vesting date, or (iii) 50% of each RSU grant vests on the first anniversary and 25% of each RSU grant vests in 6 months increment after the one year anniversary of the grant date.        
Stock-based compensation expense | $           $ 3,142,000 934,000      
Restricted Stock Units | Share Based Compensation Award Tranche One                    
Class of Stock [Line Items]                    
Vesting percentage           50.00%        
Restricted Stock Units | Share Based Compensation Award Tranche Two                    
Class of Stock [Line Items]                    
Vesting periods           6 months        
Vesting percentage           25.00%        
Restricted Stock Units | Share-based Compensation Award, Tranche, First Or Third Anniversary of Grant Date                    
Class of Stock [Line Items]                    
Vesting percentage           100.00%        
Performance Based Restricted Stock Unit                    
Class of Stock [Line Items]                    
Granted, Shares   479,000                
Stock-based compensation expense | $           $ 100,000 $ 0      
Performance-Based Stock Options                    
Class of Stock [Line Items]                    
Granted, Shares           0 0      
Oustanding, Shares         0 0   46,790    
Vesting percentage, Following achievement of performance condition         50.00%          
Performance-Based Stock Options | Keryx Biopharmaceuticals, Inc. | Merger Agreement                    
Class of Stock [Line Items]                    
Granted, Shares         233,954          
Common Stock                    
Class of Stock [Line Items]                    
Common stock, shares outstanding           130,251,440 117,122,262 121,674,568 116,887,518  
Issuance of common stock, net of issuance costs, shares           7,973,967        
Minimum | Stock Options                    
Class of Stock [Line Items]                    
Vesting periods           12 months        
Minimum | Restricted Stock Units                    
Class of Stock [Line Items]                    
Vesting periods           1 year        
Minimum | Performance-Based Stock Options                    
Class of Stock [Line Items]                    
Potential share issuable percentage         0.00%          
Maximum | Stock Options                    
Class of Stock [Line Items]                    
Vesting periods           48 months        
Maximum | Restricted Stock Units                    
Class of Stock [Line Items]                    
Vesting periods           3 years        
Maximum | Performance-Based Stock Options                    
Class of Stock [Line Items]                    
Potential share issuable percentage         100.00%          
Vesting percentage, upon achievement of performance condition         50.00%          
At The Market Equity Offering Program                    
Class of Stock [Line Items]                    
Common stock sales agreement amount | $           $ 0        
At The Market Equity Offering Program | Common Stock                    
Class of Stock [Line Items]                    
Issuance of common stock, net of issuance costs, shares           7,973,967   2,684,392    
Proceeds from the issuance of common stock, net of issuance costs | $           $ 56,700,000   $ 16,800,000    
At The Market Equity Offering Program | Maximum                    
Class of Stock [Line Items]                    
Common stock sales agreement amount | $ $ 65,000,000.0   $ 75,000,000.0              
2014 Plans                    
Class of Stock [Line Items]                    
Common stock, shares reserved for future issuance                   1,785,000
Incremental rate at which the shares reserved for issuance increase           3.00%        
2014 Plans | Stock Options | Employees                    
Class of Stock [Line Items]                    
Granted, Shares           1,714,800        
2014 Plans | Stock Options | Director                    
Class of Stock [Line Items]                    
Granted, Shares           0        
2014 Plans | Restricted Stock Units | Employees                    
Class of Stock [Line Items]                    
Granted, Shares           2,350,400        
2014 Plans | Restricted Stock Units | Director                    
Class of Stock [Line Items]                    
Granted, Shares           0        
2014 Plans | Performance Based Restricted Stock Unit | Employees                    
Class of Stock [Line Items]                    
Granted, Shares           479,000        
2014 Employee Stock Purchase Plan                    
Class of Stock [Line Items]                    
Common stock, shares reserved for future issuance           5,600,968        
Purchase price at the end of offering period           85.00%        
Offering period           6 months        
Shares issued           115,024        
Stock-based compensation expense | $           $ 157,000 $ 48,000