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Stockholders' Equity (Tables)

6 Months Ended

Jun. 30, 2017

Summary of Reserved Shares of Common Stock for Future Issuance

The Company has reserved for future issuance the following number of shares of common stock:

	June 30, 2017		December 31, 2016
Common stock options and RSU's outstanding		4,856,871		3,579,694
Shares available for issuance under the 2014 Plan ⁽¹⁾		739,579		885,328
Warrant to purchase common stock		509,611		—
Shares available for issuance under the ESPP ⁽²⁾		677,762		803,105
Total		6,783,823		5,268,127

⁽¹⁾

On January 1, 2017 and January 1, 2016, the shares reserved for future grants under the 2014 Plan increased by 1,265,863 and 986,800 shares, respectively pursuant to the 2014 Plan Evergreen Provision.

⁽²⁾

On February 28, 2016, the shares reserved for future issuance under the ESPP increased by 273,404 shares pursuant to the ESPP Evergreen Provision.

Stock-Based Compensation Expense Related to Share-Based Awards

The Company has classified its stock-based compensation expense related to share-based awards as follows:

	Three months ended				Six months ended
	June 30, 2017		June 30, 2016		June 30, 2017		June 30, 2016
	(in thousands)				(in thousands)
Research and development	$	997	$	365	$	5,171	$	757
General and administrative		1,508		857		2,762		1,716
Total	$	2,505	$	1,222	$	7,933	$	2,473

Schedule of Compensation Expense by Type of Award

Compensation expense by type of award:

	Three months ended				Six months ended
	June 30, 2017		June 30, 2016		June 30, 2017		June 30, 2016
	(in thousands)				(in thousands)
Stock options	$	1,747	$	1,021	$	3,322	$	2,149
Restricted stock		57		27		65		13
Restricted stock units		659		158		1,050		264
Employee stock purchase plan		42		16		83		47
Warrant		—		—		3,413		—
Total	$	2,505	$	1,222	$	7,933	$	2,473