Accrued Expenses

6 Months Ended

Jun. 30, 2016

5. Accrued Expenses

Accrued expenses are as follows:


	June 30, 2016		December 31, 2015
	(in thousands)
Accrued clinical	$	10,692	$	4,536
Accrued bonus		1,250		2,178
Professional fees		761		647
Accrued vacation		433		310
Accrued payroll		410		518
Accrued severance		196	—
Other		2,047		1,366
Total accrued expenses	$	15,789	$	9,555

In January 2016, the Company entered into separation agreements with two employees. During the first quarter of 2016, the Company recorded severance expense in the amount of $0.4 million, of which $0.2 million was recorded to general and administrative expense and $0.2 million was recorded to research and development expense. During the three months ended June 30, 2016, approximately $0.1 million was paid out of the severance accrual and during the six months ended June 30, 2016, approximately $0.2 was paid out of the severance accrual.