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Net Loss per Share - Computation of Basic and Diluted Net Loss per Share (Details) - USD ($)
$ / shares in Units, $ in Thousands
3 Months Ended 12 Months Ended
Dec. 31, 2020
Sep. 30, 2020
Jun. 30, 2020
Mar. 31, 2020
Dec. 31, 2019
Sep. 30, 2019
Jun. 30, 2019
Mar. 31, 2019
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Numerator:                      
Net loss $ (24,011) $ (68,845) $ 25,315 $ (119,025) $ (93,805) $ (112,994) $ (99,172) $ (96,756) $ (186,566) $ (402,727) $ (197,611)
Denominator:                      
Weighted-average shares used to compute net loss per share, basic and diluted                 60,845,550 56,576,885 49,775,223
Net loss per share, basic and diluted         $ (1.62) $ (1.96) $ (1.72) $ (1.82) $ (3.07) $ (7.12) $ (3.97)