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Net Loss per Share Attributable to Common Stockholders - Computation of Basic and Diluted Net Loss per Share (Details) (USD $)
In Thousands, except Share data, unless otherwise specified
3 Months Ended 12 Months Ended
Dec. 31, 2014
Sep. 30, 2014
Jun. 30, 2014
Mar. 31, 2014
Dec. 31, 2013
Sep. 30, 2013
Jun. 30, 2013
Mar. 31, 2013
Dec. 31, 2014
Dec. 31, 2013
Dec. 31, 2012
Numerator:                      
Net loss $ (16,738)us-gaap_NetIncomeLoss $ (15,849)us-gaap_NetIncomeLoss $ (13,585)us-gaap_NetIncomeLoss $ (13,630)us-gaap_NetIncomeLoss $ (11,317)us-gaap_NetIncomeLoss $ (8,428)us-gaap_NetIncomeLoss $ (8,590)us-gaap_NetIncomeLoss $ (6,735)us-gaap_NetIncomeLoss $ (59,802)us-gaap_NetIncomeLoss $ (35,070)us-gaap_NetIncomeLoss $ (16,334)us-gaap_NetIncomeLoss
Accretion and dividends on convertible preferred stock                 (4,808)us-gaap_PreferredStockDividendsAndOtherAdjustments (15,219)us-gaap_PreferredStockDividendsAndOtherAdjustments (3,227)us-gaap_PreferredStockDividendsAndOtherAdjustments
Net loss attributable to common stockholders $ (16,738)us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic $ (15,849)us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic $ (13,585)us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic $ (18,438)us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic $ (18,665)us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic $ (12,590)us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic $ (10,829)us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic $ (8,205)us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic $ (64,610)us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic $ (50,289)us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic $ (19,561)us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic
Denominator:                      
Weighted-average common shares outstanding                 28,755,758us-gaap_WeightedAverageNumberOfSharesOutstandingBasic 3,583,522us-gaap_WeightedAverageNumberOfSharesOutstandingBasic 3,118,798us-gaap_WeightedAverageNumberOfSharesOutstandingBasic
Less: weighted-average unvested common shares subject to repurchase                   (201,033)us-gaap_WeightedAverageNumberOfSharesCommonStockSubjectToRepurchaseOrCancellation (1,741,591)us-gaap_WeightedAverageNumberOfSharesCommonStockSubjectToRepurchaseOrCancellation
Weighted-average shares used to compute net loss per share attributable to common stockholders, basic and diluted                 28,755,758us-gaap_WeightedAverageNumberOfShareOutstandingBasicAndDiluted 3,382,489us-gaap_WeightedAverageNumberOfShareOutstandingBasicAndDiluted 1,377,207us-gaap_WeightedAverageNumberOfShareOutstandingBasicAndDiluted
Net loss per share attributable to common stockholders, basic and diluted $ (0.52)us-gaap_EarningsPerShareBasicAndDiluted $ (0.50)us-gaap_EarningsPerShareBasicAndDiluted $ (0.45)us-gaap_EarningsPerShareBasicAndDiluted $ (0.85)us-gaap_EarningsPerShareBasicAndDiluted $ (4.98)us-gaap_EarningsPerShareBasicAndDiluted $ (3.48)us-gaap_EarningsPerShareBasicAndDiluted $ (3.32)us-gaap_EarningsPerShareBasicAndDiluted $ (2.84)us-gaap_EarningsPerShareBasicAndDiluted $ (2.25)us-gaap_EarningsPerShareBasicAndDiluted $ (14.87)us-gaap_EarningsPerShareBasicAndDiluted $ (14.20)us-gaap_EarningsPerShareBasicAndDiluted