CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS (Unaudited) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2024	Sep. 30, 2023	Sep. 30, 2024	Sep. 30, 2023
Revenues:
Total revenues	$ 139,494	$ 98,052	$ 395,353	$ 306,857
Operating expenses:
Cost of sales	21,021	10,987	59,834	33,158
Research and development	170,109	157,245	510,099	487,892
Selling, general and administrative	80,351	74,917	239,115	232,966
Total operating expenses	271,481	243,149	809,048	754,016
Loss from operations	(131,987)	(145,097)	(413,695)	(447,159)
Interest income	10,731	5,881	26,956	18,135
Change in fair value of equity investments	678	(1,419)	433	(1,492)
Non-cash interest expense on liabilities for sales of future royalties	(15,712)	(17,665)	(47,519)	(48,676)
Other income (expense)	3,077	(699)	(357)	(2,380)
Loss before income taxes	(133,213)	(158,999)	(434,182)	(481,572)
Provision for income taxes	(303)	(650)	(1,616)	(1,877)
Net loss	$ (133,516)	$ (159,649)	$ (435,798)	$ (483,449)
Net loss per share, basic	$ (1.4)	$ (2.23)	$ (4.91)	$ (6.81)
Net loss per share, diluted	$ (1.4)	$ (2.23)	$ (4.91)	$ (6.81)
Shares used in computing net loss per share, Basic	95,493,996	71,664,493	88,811,157	70,987,801
Shares used in computing net loss per share, Diluted	95,493,996	71,664,493	88,811,157	70,987,801
Product sales
Revenues:
Total revenues	$ 77,251	$ 42,349	$ 213,545	$ 128,757
Royalty revenue
Revenues:
Total revenues	62,243	55,703	181,808	106,916
Collaboration and license
Revenues:
Total revenues	$ 0	$ 0	$ 0	$ 71,184