Stock Option Plan and Stock-Based Compensation (Tables)

9 Months Ended

Sep. 30, 2014

2010 Plan

Schedule of Stock-Based Compensation Expense

The stock-based compensation expense recorded related to options granted to employees and nonemployees was as follows (in thousands):

	Three Months Ended				Nine Months Ended
	September 30,				September 30,
	2014		2013		2014		2013
Research and development	$	871	$	102	$	1,561	$	304
General and administrative		890		40		1,767		220
	$	1,761	$	142	$	3,328	$	524

Restricted Common Stock (Founders Shares)

Schedule of Stock-Based Compensation Expense

The stock-based compensation expense recorded related to the founders’ shares was as follows (in thousands):

	Three Months Ended				Nine Months Ended
	September 30,				September 30,
	2014		2013		2014		2013
Research and development	$	973	$	63	$	1,208	$	160
General and administrative		1		792		4		1,050
	$	974	$	855	$	1,212	$	1,210