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Debt Obligations - 2027 Term Loan - Narrative (Details) $ in Thousands	1 Months Ended		3 Months Ended	12 Months Ended
	Mar. 31, 2022 USD ($)	Jan. 31, 2022 USD ($)	Dec. 31, 2022 USD ($)	Dec. 31, 2022 USD ($)	Sep. 14, 2022 USD ($)	Jan. 05, 2022 USD ($) tranche	Apr. 30, 2020 USD ($)	Feb. 29, 2016 USD ($)
Debt Instrument [Line Items]
Outstanding amount paid off				$ 81,750
Outstanding amount payoff				$ 109,000
2027 Term Loans
Debt Instrument [Line Items]
Debt Instrument, Interest Rate During Period			12.00%
2027 Term Loans \| Secured Overnight Financing Rate (SOFR) Overnight Index Swap Rate [Member]
Debt Instrument [Line Items]
Spread on variable rate				1.00%
Debt Instrument, Interest Rate During Period				0.26161%
2027 Term Loans \| BioPharma Credit Investments V GP LLC
Debt Instrument [Line Items]
Principal amount						$ 300,000
Number of tranches \| tranche						4
Net carrying value			$ 245,483	$ 245,483
Loan agreement covenants, minimum trailing twelve month net sales for current quarter		$ 200,000
Loan agreement covenants, minimum trailing twelve month net sales for the quarter ended March 30, 2024		210,000
Loan agreement covenants, minimum trailing twelve-month net sales for the quarter ended June 30, 2024		230,000
Loan agreement covenants, minimum trailing twelve-month net sales for the quarter ended September 30, 2024		270,000
Loan agreement covenants, minimum trailing twelve-month net sales for the quarter ended December 31, 2024 and thereafter		$ 300,000
Mandatory prepayment term		10 days
Debt discounts and issuance costs		$ 6,800
Remaining unamortized debt discount and debt offering costs			$ 4,517	$ 4,517
2027 Term Loans \| BioPharma Credit Investments V GP LLC \| Three-month LIBOR
Debt Instrument [Line Items]
Spread on variable rate		1.00%
2027 Term Loans \| Additional facility amount \| BioPharma Credit Investments V GP LLC
Debt Instrument [Line Items]
Uncommitted additional facility		$ 100,000
2027 Term Loans \| Through March 31, 2023 \| BioPharma Credit Investments V GP LLC
Debt Instrument [Line Items]
Stated interest rate		8.25%
2027 Term Loans \| Starting April 1, 2023
Debt Instrument [Line Items]
Stated interest rate			8.25%	8.25%
Tranche A Loan, funded January 5, 2022 \| BioPharma Credit Investments V GP LLC
Debt Instrument [Line Items]
Principal amount						$ 100,000
Debt discounts and issuance costs		$ 7,800
Tranche B Loan, funded no later than April 1, 2022 \| BioPharma Credit Investments V GP LLC
Debt Instrument [Line Items]
Principal amount	$ 100,000
Debt discounts and issuance costs	2,300
Convertible notes, Issuance Cost	1,000
Tranche C Loan, funded between April 1, 2022 and March 17, 2023 \| BioPharma Credit Investments V GP LLC
Debt Instrument [Line Items]
Amount not funded		50,000
Tranche D Loan, funded on September 14, 2022 \| BioPharma Credit Investments V GP LLC
Debt Instrument [Line Items]
Principal amount					$ 50,000
Convertible notes, Issuance Cost					$ 500
1.5% Convertible Senior Subordinated Notes due 2026 \| Convertible Notes
Debt Instrument [Line Items]
Principal amount							$ 230,000
Net carrying value			$ 225,575	$ 225,575
Stated interest rate							1.50%
Remaining unamortized debt discount and debt offering costs			$ 4,425	$ 4,425
Total term of the loan				3 years 3 months 18 days
Effective interest rate			2.10%	2.10%
1.5% Convertible Senior Subordinated Notes due 2026 \| BioPharma Credit Investments V GP LLC \| Scenario, Plan \| Maximum
Debt Instrument [Line Items]
Principal amount		50,000
8.2% Convertible Notes due 2022 \| Convertible Notes
Debt Instrument [Line Items]
Principal amount								$ 100,000
Stated interest rate								8.20%
Outstanding amount payoff	$ 111,100
Convertible notes, Issuance Cost								$ 800
2025 Term Loan
Debt Instrument [Line Items]
Net carrying value			$ 0	$ 0
2025 Term Loan \| Convertible Notes
Debt Instrument [Line Items]
Outstanding amount paid off		$ 81,900
Tranche A and B Loans \| BioPharma Credit Investments V GP LLC
Debt Instrument [Line Items]
Remaining unamortized debt discount and debt offering costs			$ 4,500	$ 4,500
Tranches A, B and D \| BioPharma Credit Investments V GP LLC
Debt Instrument [Line Items]
Remaining term				4 years