Condensed Consolidated Statements of Operations - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2022	Sep. 30, 2021	Sep. 30, 2022	Sep. 30, 2021
Revenue:
Net revenue	$ 45,424	$ 82,503	$ 165,690	$ 253,180
Costs and expenses:
Cost of goods sold	35,234	21,280	55,881	45,487
Research and development	45,808	54,085	170,336	312,343
Selling, general and administrative	44,831	39,925	144,860	119,661
Total costs and expenses	125,873	115,290	371,077	477,491
Loss from operations	(80,449)	(32,787)	(205,387)	(224,311)
Interest expense	(7,540)	(5,771)	(23,089)	(17,166)
Loss on debt extinguishment			(6,222)
Other income (expense), net	1,339	30	1,814	102
Loss before income taxes	(86,650)	(38,528)	(232,884)	(241,375)
Net loss	$ (86,650)	$ (38,528)	$ (232,884)	$ (241,375)
Net loss per share:
Basic net loss per share	$ (1.11)	$ (0.49)	$ (3.00)	$ (3.22)
Diluted net loss per share	$ (1.11)	$ (0.49)	$ (3.00)	$ (3.22)
Weighted-average number of shares used in computing net loss per share:
Weighted-average number of shares used in computing basic net loss per share	77,746,895	79,013,240	77,520,244	74,984,811
Weighted-average number of shares used in computing diluted net loss per share	77,746,895	79,013,240	77,520,244	74,984,811