Condensed Consolidated Statements of Operations - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021	Jun. 30, 2022	Jun. 30, 2021
Revenue:
Net revenue	$ 60,151	$ 87,643	$ 120,266	$ 170,677
Costs and expenses:
Cost of goods sold	11,277	16,696	20,647	24,207
Research and development	41,611	54,766	124,528	258,258
Selling, general and administrative	51,276	40,345	100,029	79,736
Total costs and expenses	104,164	111,807	245,204	362,201
Loss from operations	(44,013)	(24,164)	(124,938)	(191,524)
Interest expense	(6,580)	(5,747)	(15,549)	(11,395)
Loss on debt extinguishment			(6,222)
Other income, net	443	11	475	72
Loss before income taxes	(50,150)	(29,900)	(146,234)	(202,847)
Net loss	$ (50,150)	$ (29,900)	$ (146,234)	$ (202,847)
Net loss per share:
Basic net loss per share	$ (0.65)	$ (0.40)	$ (1.89)	$ (2.73)
Diluted net loss per share	$ (0.65)	$ (0.40)	$ (1.89)	$ (2.73)
Weighted-average number of shares used in computing net loss per share:
Weighted-average number of shares used in computing basic net loss per share	77,554,717	75,559,697	77,405,040	74,203,858
Weighted-average number of shares used in computing diluted net loss per share	77,554,717	75,559,697	77,405,040	74,203,858