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INCOME TAXES - Reconciliation of Statutory Federal Income Tax Rate to Company's Effective Tax Rate (Details)
12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Income Tax Disclosure [Abstract]      
Tax at federal statutory rate 34.00% 34.00% 34.00%
State taxes, net of federal benefit (0.40%) (0.10%) (0.20%)
Foreign rate differential (14.90%) (2.40%) (1.80%)
Nondeductible expenses (1.00%) (0.90%) (1.10%)
Credits 41.50% 8.50% 8.20%
Other items (1.20%) 0.20% 0.10%
Change in valuation allowance (119.50%) (37.40%) (38.60%)
Impact of U.S. tax reform (209.10%) 0.00% 0.00%
Share-based compensation 243.50% (2.40%) (2.20%)
Change in uncertain tax positions (2.40%) (0.60%) (0.50%)
Termination of warrant 29.30% 0.00% 0.00%
Total (0.20%) (1.10%) (2.10%)