The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
|
UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
|
||||||||||||||||
| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| ADMA BIOLOGICS INC | COM | 000899104 | 3,538 | 1,102,200 | SH | DFND | 1 | 1,102,200 | 0 | 0 | |
| AGILE THERAPEUTICS INC | COM | 00847L100 | 964 | 358,295 | SH | DFND | 1 | 358,295 | 0 | 0 | |
| ALPHATEC HOLDINGS INC | COM NEW | 02081G201 | 387 | 145,514 | SH | DFND | 1 | 145,514 | 0 | 0 | |
| AMARIN CORP PLC | SPONS ADR NEW | 023111206 | 4,613 | 1,150,449 | SH | DFND | 1 | 1,150,449 | 0 | 0 | |
| ANGIODYNAMICS INC | COM | 03475V101 | 28,809 | 1,732,361 | SH | DFND | 1 | 1,732,361 | 0 | 0 | |
| ANTARES PHARMA INC | COM | 036642106 | 9,026 | 4,535,647 | SH | DFND | 1 | 4,535,647 | 0 | 0 | |
| ARATANA THERAPEUTICS INC | COM | 03874P101 | 22,589 | 4,294,426 | SH | DFND | 1 | 4,294,426 | 0 | 0 | |
| AVADEL PHARMACEUTICALS PLC | SPONSORED ADR | 05337M104 | 21,252 | 2,591,721 | SH | DFND | 1 | 2,591,721 | 0 | 0 | |
| BAXTER INTL INC | COM | 071813109 | 4,221 | 65,300 | SH | DFND | 1 | 65,300 | 0 | 0 | |
| BIODELIVERY SCIENCES INTL IN | COM | 09060J106 | 13,671 | 4,634,119 | SH | DFND | 1 | 4,634,119 | 0 | 0 | |
| CATALYST PHARMACEUTICALS INC | COM | 14888U101 | 27,750 | 7,097,300 | SH | DFND | 1 | 7,097,300 | 0 | 0 | |
| CIDARA THERAPEUTICS INC | COM | 171757107 | 5,830 | 857,397 | SH | DFND | 1 | 857,397 | 0 | 0 | |
| COGENTIX MED INC | COM | 19243A104 | 2,113 | 670,812 | SH | DFND | 1 | 670,812 | 0 | 0 | |
| CONTRAFECT CORP | COM | 212326102 | 1,244 | 1,231,666 | SH | DFND | 1 | 1,231,666 | 0 | 0 | |
| CORIUM INTL INC | COM | 21887L107 | 32,985 | 3,432,326 | SH | DFND | 1 | 3,432,326 | 0 | 0 | |
| GW PHARMACEUTICALS PLC | ADS | 36197T103 | 16,228 | 122,930 | SH | DFND | 1 | 122,930 | 0 | 0 | |
| HERON THERAPEUTICS INC | COM | 427746102 | 36,716 | 2,028,518 | SH | DFND | 1 | 2,028,518 | 0 | 0 | |
| IDERA PHARMACEUTICALS INC | COM NEW | 45168K306 | 4,285 | 2,030,604 | SH | DFND | 1 | 2,030,604 | 0 | 0 | |
| IGNYTA INC | COM | 451731103 | 30,708 | 1,150,119 | SH | DFND | 1 | 1,150,119 | 0 | 0 | |
| INTEGRA LIFESCIENCES HLDGS C | COM NEW | 457985208 | 15,823 | 330,600 | SH | DFND | 1 | 330,600 | 0 | 0 | |
| IOVANCE BIOTHERAPEUTICS INC | COM | 462260100 | 18,725 | 2,340,611 | SH | DFND | 1 | 2,340,611 | 0 | 0 | |
| LA JOLLA PHARMACEUTICAL CO | COM PAR $.0001 2 | 503459604 | 33,141 | 1,029,866 | SH | DFND | 1 | 1,029,866 | 0 | 0 | |
| MEDICINES CO | COM | 584688105 | 10,015 | 366,300 | SH | DFND | 1 | 366,300 | 0 | 0 | |
| MIRATI THERAPEUTICS INC | COM | 60468T105 | 44,671 | 2,447,746 | SH | DFND | 1 | 2,447,746 | 0 | 0 | |
| NANOSTRING TECHNOLOGIES INC | COM | 63009R109 | 747 | 100,000 | SH | DFND | 1 | 100,000 | 0 | 0 | |
| NATUS MEDICAL INC DEL | COM | 639050103 | 7,808 | 204,400 | SH | DFND | 1 | 204,400 | 0 | 0 | |
| NOVELION THERAPEUTICS INC | COM NEW | 67001K202 | 6,079 | 1,948,554 | SH | DFND | 1 | 1,948,554 | 0 | 0 | |
| NUVASIVE INC | COM | 670704105 | 4,802 | 82,100 | SH | DFND | 1 | 82,100 | 0 | 0 | |
| OVASCIENCE INC | COM | 69014Q101 | 770 | 550,000 | SH | DFND | 1 | 550,000 | 0 | 0 | |
| PARATEK PHARMACEUTICALS INC | COM | 699374302 | 7,271 | 406,207 | SH | DFND | 1 | 406,207 | 0 | 0 | |
| PERNIX THERAPEUTICS HLDGS IN | DBCV 4.250% 4/0 | 71426VAK4 | 5,989 | 15,000,000 | SH | DFND | 1 | 15,000,000 | 0 | 0 | |
| RECRO PHARMA INC | COM | 75629F109 | 22,533 | 2,436,025 | SH | DFND | 1 | 2,436,025 | 0 | 0 | |
| REGULUS THERAPEUTICS INC | COM | 75915K101 | 1,570 | 1,509,342 | SH | DFND | 1 | 1,509,342 | 0 | 0 | |
| RETROPHIN INC | COM | 761299106 | 34,594 | 1,641,868 | SH | DFND | 1 | 1,641,868 | 0 | 0 | |
| RETROPHIN INC | COM | 761299106 | 1,094 | 51,900 | SH | Call | DFND | 1 | 51,900 | 0 | 0 |
| STRATA SKIN SCIENCES INC | COM NEW | 86272A206 | 250 | 203,346 | SH | DFND | 1 | 203,346 | 0 | 0 | |
| TELIGENT INC NEW | COM | 87960W104 | 6,989 | 1,925,415 | SH | DFND | 1 | 1,925,415 | 0 | 0 | |
| TETRAPHASE PHARMACEUTICALS I | COM | 88165N105 | 5,601 | 889,100 | SH | DFND | 1 | 889,100 | 0 | 0 | |
| VERACYTE INC | COM | 92337F107 | 4,874 | 746,358 | SH | DFND | 1 | 746,358 | 0 | 0 | |
| VERICEL CORP | COM | 92346J108 | 472 | 86,558 | SH | DFND | 1 | 86,558 | 0 | 0 | |
| ZOGENIX INC | COM NEW | 98978L204 | 18,306 | 457,080 | SH | DFND | 1 | 457,080 | 0 | 0 | |
| ENDO INTL PLC | SHS | G30401106 | 18,928 | 2,442,323 | SH | DFND | 1 | 2,442,323 | 0 | 0 | |
| HORIZON PHARMA PLC | SHS | G4617B105 | 44,063 | 3,018,021 | SH | DFND | 1 | 3,018,021 | 0 | 0 | |
| HORIZON PHARMA PLC | SHS | G4617B105 | 4,380 | 300,000 | SH | Call | DFND | 1 | 300,000 | 0 | 0 |
| STRONGBRIDGE BIOPHARMA PLC | SHS USD | G85347105 | 23,104 | 3,186,695 | SH | DFND | 1 | 3,186,695 | 0 | 0 | |
| MEDIWOUND LTD | ORD SHS | M68830104 | 2,225 | 500,000 | SH | DFND | 1 | 500,000 | 0 | 0 | |