Acquisition of Flame Biosciences (Details)		1 Months Ended	3 Months Ended
	Jan. 17, 2023 USD ($) shares	Jan. 31, 2023 USD ($) $ / shares shares	Mar. 31, 2023 USD ($) $ / shares shares	Dec. 31, 2022 USD ($)
Asset Acquisition [Table]
Cash			$ 102,038,000	$ 65,500,000
Period to held to special meeting			6 months
Change in fair value of warrant liability			$ 50,000
January 2023 Common Stock Warrants
Asset Acquisition [Table]
Shares issuable upon exercise of warrants | shares		65,301
Exercise price per share | $ / shares		$ 0.68	$ 0.680
Series X Preferred Stock
Asset Acquisition [Table]
Shares issuable upon exercise of warrants | shares			443
Conversion ratio			1,000
Series X Preferred Stock | January 2023 Series X Preferred Stock Warrants
Asset Acquisition [Table]
Shares issuable upon exercise of warrants | shares		443	443
Conversion ratio		1,000	1,000
Exercise price per share | $ / shares		$ 678.48	$ 678.48
Flame
Asset Acquisition [Table]
Percentage of outstanding ordinary shares acquired	100.00%
Number of shares issued | shares	19,729,010
Holdback shares	15,604
Purchase price	$ 79,016,000
Working capital items	928,000
Acquired I P R & D	(29,582,000)
Cash	50,362,000		$ 29,582,000
Direct and incremental costs of the asset acquisition	$ 1,393,000
Percentage of contingent merger consideration on after tax net proceeds	80.00%
Period to held to special meeting			6 months
Period for obtaining stockholder approval from the date of issuance			6 months
Flame | January 2023 Common Stock Warrants
Asset Acquisition [Table]
Shares issuable upon exercise of warrants | shares	65,301
Adjustment for amortization		$ 0.68
Flame | January 2023 Series X Preferred Stock Warrants
Asset Acquisition [Table]
Conversion ratio		1,000
Flame | Series X Non Voting Convertible Preferred Stock
Asset Acquisition [Table]
Number of shares issued | shares	136,248
Flame | Series X Preferred Stock
Asset Acquisition [Table]
Conversion ratio	1,000	1,000	1,000
Flame | Series X Preferred Stock | January 2023 Common Stock Warrants
Asset Acquisition [Table]
Shares issuable upon exercise of warrants | shares		65,301
Flame | Series X Preferred Stock | January 2023 Series X Preferred Stock Warrants
Asset Acquisition [Table]
Shares issuable upon exercise of warrants | shares	443	443
Exercise price per share | $ / shares		$ 678.48