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Note 8 - Stock-based Compensation (Tables)
9 Months Ended
Sep. 30, 2018
Notes Tables  
Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
   
Three Months Ended
September
30,
   
Nine
Months Ended September
30,
 
   
2017
   
2017
 
Expected term (years)
   
5.6
     
5.9
 
Expected volatility
   
63.6
%
   
57.2
%
Risk-free interest rate
   
1.8
%
   
2.2
%
Dividend rate
   
     
 
Schedule of Share-based Payment Award, Employee Stock Purchase Plan, Valuation Assumptions [Table Text Block]
   
Three Months Ended

September 30, 2017
   
Nine Months Ended
September
30, 2017
 
Expected term (years)
   
0.5
     
0.5
 
Expected volatility
   
117.1
%
   
109.2
%
Risk-free interest rate
   
0.94
%
   
0.78
%
Dividend rate