0001209191-18-050553.txt : 20180911 0001209191-18-050553.hdr.sgml : 20180911 20180911180841 ACCESSION NUMBER: 0001209191-18-050553 CONFORMED SUBMISSION TYPE: 4 PUBLIC DOCUMENT COUNT: 1 CONFORMED PERIOD OF REPORT: 20180910 FILED AS OF DATE: 20180911 DATE AS OF CHANGE: 20180911 REPORTING-OWNER: OWNER DATA: COMPANY CONFORMED NAME: Primiano Christopher Brett CENTRAL INDEX KEY: 0001603510 FILING VALUES: FORM TYPE: 4 SEC ACT: 1934 Act SEC FILE NUMBER: 001-36167 FILM NUMBER: 181065672 MAIL ADDRESS: STREET 1: C/O KARYOPHARM THERAPEUTICS INC. STREET 2: 85 WELLS AVENUE, SECOND FLOOR CITY: NEWTON STATE: MA ZIP: 02459 ISSUER: COMPANY DATA: COMPANY CONFORMED NAME: Karyopharm Therapeutics Inc. CENTRAL INDEX KEY: 0001503802 STANDARD INDUSTRIAL CLASSIFICATION: PHARMACEUTICAL PREPARATIONS [2834] IRS NUMBER: 263931704 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 BUSINESS ADDRESS: STREET 1: 85 WELLS AVENUE STREET 2: SECOND FLOOR CITY: NEWTON STATE: MA ZIP: 02459 BUSINESS PHONE: 617-658-0600 MAIL ADDRESS: STREET 1: 85 WELLS AVENUE STREET 2: SECOND FLOOR CITY: NEWTON STATE: MA ZIP: 02459 4 1 doc4.xml FORM 4 SUBMISSION X0306 4 2018-09-10 0 0001503802 Karyopharm Therapeutics Inc. KPTI 0001603510 Primiano Christopher Brett C/O KARYOPHARM THERAPEUTICS INC. 85 WELLS AVENUE NEWTON MA 02459 0 1 0 0 EVP, CBO, GC & Secretary Common Stock 2018-09-10 4 M 0 5000 6.54 A 7881 D Common Stock 2018-09-10 4 M 0 5000 10.39 A 12881 D Common Stock 2018-09-10 4 S 0 10000 18.9046 D 2881 D Stock Option (right to buy) 6.54 2018-09-10 4 M 0 5000 0.00 D 2026-01-14 Common Stock 5000 18000 D Stock Option (right to buy) 10.39 2018-09-10 4 M 0 5000 0.00 D 2027-01-19 Common Stock 5000 113000 D These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. Represents the weighted average sale price. These shares were sold in multiple transactions at prices ranging from $18.27 to $19.08, inclusive. The reporting person undertakes to provide upon request by the U.S. Securities and Exchange Commission staff, the issuer or a security holder of the issuer, full information regarding the number of shares sold at each separate price. This option, representing a right to purchase a specified number of shares, vested as to 25% of the shares on January 15, 2017, with the remaining 75% vesting in 36 equal monthly installments thereafter. This option, representing a right to purchase a specified number of shares, vested as to 25% of the shares on January 20, 2018, with the remaining 75% vesting in 36 equal monthly installments thereafter. /s/ Christopher B. Primiano 2018-09-11