| Summary of Unaudited Quarterly Financial Data |
The following table summarizes the unaudited quarterly financial
data for the last two fiscal years (in thousands).
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Year Ended December 31, 2017
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|
First
Quarter |
|
|
Second
Quarter |
|
|
Third
Quarter |
|
|
Fourth
Quarter |
|
|
License and other revenue
|
|
$ |
68 |
|
|
$ |
3 |
|
|
$ |
— |
|
|
$ |
1,534 |
|
|
Total operating expenses
|
|
$ |
30,347 |
|
|
$ |
29,755 |
|
|
$ |
31,055 |
|
|
$ |
40,986 |
|
|
Loss from operations
|
|
$ |
(30,279 |
) |
|
$ |
(29,752 |
) |
|
$ |
(31,055 |
) |
|
$ |
(39,452 |
) |
|
Total other income (expense)
|
|
$ |
385 |
|
|
$ |
383 |
|
|
$ |
428 |
|
|
$ |
421 |
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|
Net loss
|
|
$ |
(29,917 |
) |
|
$ |
(29,387 |
) |
|
$ |
(30,640 |
) |
|
$ |
(39,040 |
) |
|
Net loss per share, basic and diluted
|
|
$ |
(0.71 |
) |
|
$ |
(0.64 |
) |
|
$ |
(0.65 |
) |
|
$ |
(0.80 |
) |
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|
|
|
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|
Year Ended December 31, 2016
|
|
First
Quarter |
|
|
Second
Quarter |
|
|
Third
Quarter |
|
|
Fourth
Quarter |
|
|
Contract and grant revenue
|
|
$ |
— |
|
|
$ |
59 |
|
|
$ |
48 |
|
|
$ |
47 |
|
|
Total operating expenses
|
|
$ |
27,349 |
|
|
$ |
30,535 |
|
|
$ |
25,790 |
|
|
$ |
27,212 |
|
|
Loss from operations
|
|
$ |
(27,349 |
) |
|
$ |
(30,476 |
) |
|
$ |
(25,742 |
) |
|
$ |
(27,165 |
) |
|
Total other income (expense)
|
|
$ |
290 |
|
|
$ |
318 |
|
|
$ |
317 |
|
|
$ |
369 |
|
|
Net loss
|
|
$ |
(27,059 |
) |
|
$ |
(30,158 |
) |
|
$ |
(25,425 |
) |
|
$ |
(26,935 |
) |
|
Net loss per share, basic and diluted
|
|
$ |
(0.75 |
) |
|
$ |
(0.84 |
) |
|
$ |
(0.69 |
) |
|
$ |
(0.65 |
) |
|