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Net Loss Per Share - Schedule of Potentially Dilutive Securities Were Excluded From The Calculation of Diluted Net Loss Per Share Due to Their Anti-Dilutive Effect (Detail) - shares
3 Months Ended 9 Months Ended
Sep. 30, 2016
Sep. 30, 2015
Sep. 03, 2016
Sep. 30, 2015
Outstanding Stock Options [Member]        
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]        
Dilutive securities excluded from the calculation of diluted net loss per share due to anti-dilutive effect (in shares) 5,557,752 4,511,561 5,557,752 4,511,561
Unvested Restricted Stock Units [Member]        
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]        
Dilutive securities excluded from the calculation of diluted net loss per share due to anti-dilutive effect (in shares) 451,600   451,600