Condensed Consolidated Statements of Cash Flows (unaudited) - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2024	Sep. 30, 2023
Operating activities
Net loss	$ (45,642)	$ (101,262)
Adjustments to reconcile net loss to net cash used in operating activities:
Stock-based compensation expense	14,562	16,527
Depreciation and amortization	259	453
Amortization of debt issuance costs and discounts	4,012	597
Net amortization of premiums and discounts on investments	(2,112)	(3,077)
Gain on extinguishment of debt	(44,702)	0
Change in fair value of embedded derivatives and common stock warrants	(18,343)	0
Changes in operating assets and liabilities:
Accounts receivable, net	(4,816)	9,163
Inventory	(1,629)	1,119
Prepaid expenses and other assets	(2,933)	5,612
Operating lease right-of-use assets	1,690	1,442
Accounts payable	2,660	(1,830)
Accrued expenses and other liabilities	(2,253)	(776)
Operating lease liabilities	(2,429)	(2,106)
Net cash used in operating activities	(101,676)	(74,138)
Investing activities
Proceeds from maturities of investments	138,187	123,688
Purchases of investments	(57,316)	(142,591)
Purchases of property and equipment	(195)	0
Net cash provided by (used in) investing activities	80,676	(18,903)
Financing activities
Proceeds from issuance of senior secured term loan	83,300	0
Proceeds from the exercise of stock options and shares issued under employee stock purchase plan	772	860
Payment of debt issuance costs	(2,588)	0
Payment of deferred royalty obligation	(40,518)	0
Net cash provided by financing activities	40,966	860
Effect of exchange rate on cash, cash equivalents and restricted cash	9	(123)
Net increase (decrease) in cash, cash equivalents and restricted cash	19,975	(92,304)
Cash, cash equivalents and restricted cash at beginning of period	53,192	136,885
Cash, cash equivalents and restricted cash at end of period	73,167	44,581
Reconciliation of cash, cash equivalents and restricted cash reported within the condensed consolidated balance sheets
Cash and cash equivalents	72,828	43,655
Short-term restricted cash	33	545
Long-term restricted cash	306	381
Total cash, cash equivalents and restricted cash	73,167	44,581
Supplemental disclosures:
Cash paid for interest on deferred royalty obligation	18,926	12,225
Cash paid for interest on convertible debt and term loan	11,472	2,588
Cash paid for amounts included in the measurement of operating lease liabilities	2,844	2,770
Convertible senior notes due 2029 issued with warrants to purchase 45,776,213 shares of common stock in exchange for a $148.0 million reduction of convertible senior notes due 2025	111,000	0
Senior secured term loan issued in exchange for a $14.7 million reduction of deferred royalty obligation	15,000	0
Issuance of common stock used to settle a financial advisory fee related to financing activities	7,697
Convertible senior notes due 2029 issued in exchange for a $5.0 million reduction of deferred royalty obligation	$ 5,000	$ 0