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Commitments and Contingencies - Additional Information (Detail)
$ in Millions
12 Months Ended
Dec. 31, 2021
USD ($)
ft²
Dec. 31, 2020
USD ($)
Dec. 31, 2019
USD ($)
Leases [Line Items]      
Operating lease cost $ 2.8 $ 2.8 $ 2.8
Lease term 3 years 9 months 18 days    
Operating lease discount rate 11.00%    
Common Area Maintenance [Member]      
Leases [Line Items]      
Operating lease cost $ 0.9 $ 1.0 $ 0.9
Office and Research Space Lease [Member]      
Leases [Line Items]      
Office and laboratory space leased | ft² 98,502    
Security deposit in the form of a letter of credit $ 0.6