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Subsequent Events - Additional Information (Details) - USD ($)
12 Months Ended
Mar. 01, 2016
Dec. 31, 2015
Jan. 20, 2016
Subsequent Event [Line Items]      
Lease expiration date   Jan. 31, 2019  
Subsequent Event | Lease Termination      
Subsequent Event [Line Items]      
Lease expiration date Nov. 30, 2016    
Collaborative Arrangement | Bristol Myers Squibb Company | Subsequent Event | Achieving Third Targets Selected By Counterparty      
Subsequent Event [Line Items]      
Contingent milestone payments receivable     $ 10,000,000