STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($) $ in Thousands	3 Months Ended			6 Months Ended	9 Months Ended	12 Months Ended
	Sep. 30, 2022	Jun. 30, 2022	Mar. 31, 2022	Jun. 30, 2022	Sep. 30, 2022	Dec. 31, 2022	Dec. 31, 2021
Statement of Comprehensive Income [Abstract]
Revenue	$ 11,147	$ 12,853	$ 9,040	$ 21,893	$ 33,040	$ 53,163	$ 37,312
Type of Revenue [Extensible List]						us-gaap:LicenseAndServiceMember	us-gaap:LicenseAndServiceMember
Operating expenses:
Research and development	30,367	31,159	30,559	61,718	92,085	$ 111,649	$ 114,194
General and administrative	10,490	11,748	10,543	22,291	32,781	42,849	39,160
Total operating expenses	40,857	42,907	41,102	84,009	124,866	154,498	153,354
Loss from operations	(29,710)	(30,054)	(32,062)	(62,116)	(91,826)	(101,335)	(116,042)
Interest income	616	262	68	330	946	1,678	255
Other income (expense), net	30	296	13	309	339	340	(83)
Loss before income taxes	(29,064)	(29,496)	(31,981)	(61,477)	(90,541)	(99,317)	(115,870)
Benefit from income taxes	0	0	0	0	0	0	0
Net loss	(29,064)	(29,496)	(31,981)	(61,477)	(90,541)	(99,317)	(115,870)
Other comprehensive income (loss):
Unrealized gain (loss) on available-for-sale investments, net of tax	367	(243)	(677)	(920)	(553)	252	(195)
Total comprehensive loss	$ (28,697)	$ (29,739)	$ (32,658)	$ (62,397)	$ (91,094)	$ (99,065)	$ (116,065)
Net loss per share, Basic	$ (0.44)	$ (0.45)	$ (0.49)	$ (0.94)	$ (1.38)	$ (1.51)	$ (1.81)
Net loss per share, Diluted	$ (0.44)	$ (0.45)	$ (0.49)	$ (0.94)	$ (1.38)	$ (1.51)	$ (1.81)
Shares used to compute net loss per share, Basic	65,912,334	65,542,762	65,393,691	65,468,638	65,618,162	65,739,844	64,146,848
Shares used to compute net loss per share, Diluted	65,912,334	65,542,762	65,393,691	65,468,638	65,618,162	65,739,844	64,146,848