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Stock-Based Compensation (Tables)
9 Months Ended
Sep. 30, 2022
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]  
Schedule of Activities Under Company's Stock Option Plans

Activities for the Company’s stock option plans for the nine months ended September 30, 2022 were as follows:

 

 

 

Options Outstanding

 

 

 

Number of
 Options

 

 

Weighted-
Average
Exercise Price
Per Share

 

Balances at December 31, 2021

 

 

12,192,216

 

 

$

9.42

 

Options granted

 

 

4,962,418

 

 

 

2.94

 

Options exercised

 

 

(100,990

)

 

 

0.98

 

Option forfeited/expired

 

 

(2,792,227

)

 

 

6.95

 

Balances at September 30, 2022

 

 

14,261,417

 

 

$

7.71

 

Total Stock-based Compensation Recognized

Total stock-based compensation recorded related to options, TRSUs, PSUs and the ESPP was as follows:

 

 

 

Three Months Ended

 

 

Nine Months Ended

 

 

 

September 30,

 

 

September 30,

 

 

 

2022

 

 

2021

 

 

2022

 

 

2021

 

 

 

(in thousands)

 

Stock-based compensation expense:

 

 

 

 

 

 

 

 

 

 

 

 

Research and development

 

$

931

 

 

$

1,328

 

 

$

5,928

 

 

$

4,213

 

General and administrative

 

 

1,764

 

 

 

1,836

 

 

 

4,627

 

 

 

5,410

 

Total stock-based compensation expense

 

$

2,695

 

 

$

3,164

 

 

$

10,555

 

 

$

9,623

 

 

Time based RSU  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]  
Schedule of Company's TRSU Activities

Activities for the Company’s TRSUs for the nine months ended September 30, 2022 were as follows:

 

 

 

Number of
Shares

 

 

Weighted Average Grant Date Fair Value Per Share

 

 

 

 

 

 

 

 

Balance at December 31, 2021

 

 

433,250

 

 

$

5.34

 

RSUs awarded

 

 

1,314,210

 

 

 

2.74

 

RSUs cancelled

 

 

(348,152

)

 

 

4.58

 

Balance at September 30, 2022

 

 

1,399,308

 

 

$

3.08

 

Performance based RSU  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]  
Schedule of Activities for Company's PSUs Activities for the Company’s PSUs for the nine months ended September 30, 2022 were as follows:

 

 

 

Number of
Shares

 

 

Weighted Average Grant Date Fair Value Per Share

 

 

 

 

 

 

 

 

Balance at December 31, 2021

 

 

435,000

 

 

$

5.34

 

PSUs awarded

 

 

250,000

 

 

 

1.59

 

PSUs vested

 

 

(193,750

)

 

 

5.34

 

PSUs cancelled

 

 

(93,750

)

 

 

5.34

 

Balance at September 30, 2022

 

 

397,500

 

 

$

2.98