CONDENSED STATEMENTS OF STOCKHOLDERS' EQUITY - USD ($) $ in Thousands	Total		Common Stock	Additional Paid-in Capital	Accumulated Other Comprehensive Loss	Accumulated Deficit
Beginning balance at Dec. 31, 2020	$ 49,803		$ 1	$ 499,964	$ (47)	$ (450,115)
Beginning balance, shares at Dec. 31, 2020			48,251,819
Issuance of common stock in follow-on offering, net of issuance costs	107,712			107,712
Issuance of common stock in follow-on offering, net of issuance costs, shares			16,428,571
Exercise of stock options	1,023			1,023
Exercise of stock options, shares			322,507
Stock-based compensation	3,034			3,034
Other comprehensive income (loss)	4				4
Net loss	(15,554)					(15,554)
Ending balance at Mar. 31, 2021	146,022		$ 1	611,733	(43)	(465,669)
Ending balance, shares at Mar. 31, 2021			65,002,897
Beginning balance at Dec. 31, 2020	49,803		$ 1	499,964	(47)	(450,115)
Beginning balance, shares at Dec. 31, 2020			48,251,819
Other comprehensive income (loss)	62
Net loss	(34,797)
Ending balance at Jun. 30, 2021	130,953		$ 1	615,849	15	(484,912)
Ending balance, shares at Jun. 30, 2021			65,157,003
Beginning balance at Mar. 31, 2021	146,022		$ 1	611,733	(43)	(465,669)
Beginning balance, shares at Mar. 31, 2021			65,002,897
Exercise of stock options	173			173
Exercise of stock options, shares			68,971
Issuance of common stock under the ESPP	518			518
Issuance of common stock under the ESPP, shares			85,135
Stock-based compensation	3,425			3,425
Other comprehensive income (loss)	58				58
Net loss	(19,243)					(19,243)
Ending balance at Jun. 30, 2021	130,953		$ 1	615,849	15	(484,912)
Ending balance, shares at Jun. 30, 2021			65,157,003
Beginning balance at Dec. 31, 2021	89,379	[1]	$ 1	623,344	(242)	(533,724)
Beginning balance, shares at Dec. 31, 2021			65,392,758
Exercise of stock options	7			7
Exercise of stock options, shares			5,597
Stock-based compensation	3,370			3,370
Other comprehensive income (loss)	(677)				(677)
Net loss	(23,885)					(23,885)
Ending balance at Mar. 31, 2022	68,194		$ 1	626,721	(919)	(557,609)
Ending balance, shares at Mar. 31, 2022			65,398,355
Beginning balance at Dec. 31, 2021	$ 89,379	[1]	$ 1	623,344	(242)	(533,724)
Beginning balance, shares at Dec. 31, 2021			65,392,758
Exercise of stock options, shares	100,990
Other comprehensive income (loss)	$ (920)
Net loss	(48,069)
Ending balance at Jun. 30, 2022	48,708		$ 1	631,662	(1,162)	(581,793)
Ending balance, shares at Jun. 30, 2022			65,756,492
Beginning balance at Mar. 31, 2022	68,194		$ 1	626,721	(919)	(557,609)
Beginning balance, shares at Mar. 31, 2022			65,398,355
Exercise of stock options	91			91
Exercise of stock options, shares			95,393
Issuance of common stock under the ESPP	360			360
Issuance of common stock under the ESPP, shares			262,744
Stock-based compensation	4,490			4,490
Other comprehensive income (loss)	(243)				(243)
Net loss	(24,184)					(24,184)
Ending balance at Jun. 30, 2022	$ 48,708		$ 1	$ 631,662	$ (1,162)	$ (581,793)
Ending balance, shares at Jun. 30, 2022			65,756,492

[1] The condensed balance sheet as of December 31, 2021 was derived from the audited financial statements included in the Company's Annual Report on Form 10-K for the year ended December 31, 2021.