Commitments and Contingencies - Additional Information (Details) € in Thousands		1 Months Ended									3 Months Ended		9 Months Ended
	May 16, 2022 USD ($)	Sep. 30, 2022 USD ($)	Jan. 31, 2022 USD ($)	Oct. 31, 2020 USD ($)	Jul. 31, 2019 USD ($)	Dec. 31, 2014 USD ($) LicensedProduct	Jan. 31, 2014 USD ($)	Sep. 30, 2013 USD ($)	Jul. 31, 2011 USD ($)	Nov. 30, 2009 EUR (€)	Sep. 30, 2024 USD ($) OperatingLease	Sep. 30, 2023 USD ($)	Sep. 30, 2024 USD ($) OperatingLease	Sep. 30, 2023 USD ($)
Lessee Lease Description [Line Items]
Estimated payments due											$ 28,468,000		$ 28,468,000
Operating lease liabilities											19,084,000		19,084,000
Research and development expenses											$ 17,036,000	$ 15,428,000	50,968,000	$ 44,952,000
National Institute of Health
Lessee Lease Description [Line Items]
License issue royalty fee								$ 100,000
Sales milestone payments								600,000
Development and regulatory milestone payments								$ 700,000
Patent licensing reimbursement fees													30,000.00
Expenses for patent licensing fees													0	0
Royalty Bearing Patent License Agreement
Lessee Lease Description [Line Items]
Expenses													100,000	0
License agreement term										10 years
Royalty Bearing Patent License Agreement | IND Filings
Lessee Lease Description [Line Items]
Potential milestone payments | €										€ 10
Clearside
Lessee Lease Description [Line Items]
Expenses													0	400,000
Upfront payment					$ 100,000
Royalties on net sales					20.00%
License agreement expiration period					10 years
Clearside | Maximum
Lessee Lease Description [Line Items]
Aggregate milestones payment					$ 21,000,000
LI-COR, Inc. | 2014 Exclusive Agreement
Lessee Lease Description [Line Items]
One-time upfront license issuance fee							$ 100,000
Research and development expenses													0	0
License agreement term							10 years
LI-COR, Inc. | 2014 Exclusive Agreement | Maximum
Lessee Lease Description [Line Items]
Aggregate milestone payments							$ 200,000
LI-COR, Inc. | 2014 Non- Exclusive Agreement
Lessee Lease Description [Line Items]
License issue fee						$ 30,000.00
Milestone payments													0	0
LI-COR, Inc. | 2014 Non- Exclusive Agreement | Maximum
Lessee Lease Description [Line Items]
Payments for development and commercial milestones						$ 400,000
Life Technologies
Lessee Lease Description [Line Items]
Number of licensed products | LicensedProduct						5
Initial license fee						$ 100,000
Initial license fee for first licensed product		$ 400,000
Initial license fee for additional licensed product		500,000
Payment for sublicense		200,000
Payment for use of cell line document package		30,000.00
Annual development fee						100,000
Non-refundable, Non- creditable fee						300,000
Change of control fees		500,000				200,000
One time perpetual license agreement fee			$ 50,000.00
Expenses													0	0
Expense related to agreement including sublicense													0	0
Dr. John Schiller | 2014 Non- Exclusive Agreement
Lessee Lease Description [Line Items]
Required amendment payment		$ 40,000.00
Required amendment payment due period		30 days
Dr. John Schiller | Collaboration Research and Development Agreement
Lessee Lease Description [Line Items]
Annual development fee									$ 30,000.00
Agreement term									2 years
First payment due									30 days
Subsequent payments due									30 days
Research collaboration fees													0	0
Required amendment payment				$ 40,000.00
Required amendment payment due period				30 days
Dr. John Schiller | Collaboration Research and Development Agreement | 10th Anniversary
Lessee Lease Description [Line Items]
Required amendment payment		$ 30,000.00		$ 30,000.00
Required amendment payment due period		30 days		30 days
Dr. John Schiller | Collaboration Research and Development Agreement | Eighth Amendment
Lessee Lease Description [Line Items]
Expenses													$ 0	$ 30,000.00
Rakuten | 2014 Non- Exclusive Agreement
Lessee Lease Description [Line Items]
License issue fee						30,000.00
Rakuten | 2014 Non- Exclusive Agreement | Maximum
Lessee Lease Description [Line Items]
License issue fee						$ 300,000
Office and Laboratory Facility
Lessee Lease Description [Line Items]
Number of operating lease | OperatingLease											1		1
Estimated payments due	$ 35,200,000
Lease commencement date	Aug. 01, 2022
Operating lease, option to extend term	7 years
Letters of credit	$ 800,000
Maximum reimbursement cost	$ 500,000
Incurred of expenses related to expansion													$ 500,000