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Other Non-Current Liabilities - Additional Information (Detail)
1 Months Ended 6 Months Ended 12 Months Ended
Jul. 31, 2016
USD ($)
Jun. 30, 2017
EUR (€)
Dec. 31, 2016
USD ($)
Jun. 30, 2017
USD ($)
Aug. 31, 2015
EUR (€)
Line Of Credit Facility [Line Items]          
Financing arrangement included in other noncurrent liabilities     $ 386,000 $ 369,000  
The Alpha-1 Project, Inc. [Member]          
Line Of Credit Facility [Line Items]          
Proceeds from financing arrangement     $ 100,000    
Financing arrangement included in other noncurrent liabilities       $ 100,000  
The Alpha-1 Project, Inc. [Member] | Maximum [Member]          
Line Of Credit Facility [Line Items]          
Potential milestone earnings $ 300,000        
Expected percentage of milestone repayments 450.00%        
BPI France [Member]          
Line Of Credit Facility [Line Items]          
Interest free conditional advance, maximum borrowing capacity | €         € 500,000
Interest free conditional advance, frequency of payments   Quarterly      
Interest free conditional advance, periodic payment | €   € 25,000      
Interest free conditional advance, beginning date of periodic payment   Sep. 30, 2017      
Interest free conditional advance, ending date of periodic payment   Jun. 30, 2022      
Interest free conditional advance, imputed interest rate       7.00%  
Interest free conditional advance       $ 400,000  
BPI France [Member] | Other Noncurrent Liabilities [Member]          
Line Of Credit Facility [Line Items]          
Interest free conditional advance       300,000  
BPI France [Member] | Accrued Expenses and Other Current Liabilities [Member]          
Line Of Credit Facility [Line Items]          
Interest free conditional advance       $ 100,000