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Property and Equipment, Net - Schedule of Property and Equipment, Net (Detail) - USD ($)
$ in Thousands
Jun. 30, 2017
Dec. 31, 2016
Property, Plant and Equipment [Line Items]    
Total property and equipment $ 7,442 $ 6,763
Less accumulated depreciation and amortization (3,644) (2,594)
Property and equipment, net 3,798 4,169
Computer Equipment and Software [Member]    
Property, Plant and Equipment [Line Items]    
Total property and equipment 447 300
Laboratory Equipment [Member]    
Property, Plant and Equipment [Line Items]    
Total property and equipment 4,838 4,285
Furniture and Fixtures [Member]    
Property, Plant and Equipment [Line Items]    
Total property and equipment 552 552
Leasehold Improvements [Member]    
Property, Plant and Equipment [Line Items]    
Total property and equipment 1,541 1,522
Construction in Progress [Member]    
Property, Plant and Equipment [Line Items]    
Total property and equipment $ 64 $ 104