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Warrants - Additional Information (Detail) - USD ($)
1 Months Ended 3 Months Ended 12 Months Ended
Oct. 15, 2015
Aug. 05, 2014
Jul. 31, 2016
May 31, 2014
Sep. 30, 2016
Dec. 31, 2016
Dec. 31, 2014
Dec. 31, 2015
Mar. 31, 2014
Aug. 31, 2012
Class of Warrant or Right [Line Items]                    
Fair value of common stock price per share           $ 17.00        
Contractual term of warrant           1 year 1 month 6 days        
Fair value of obligation risk free interest rate           0.10%        
Fair value of obligation expected volatility rate           70.00%        
Fair value of obligation expected dividend yield           0.00%        
Common stock and preferred stock exercised for cash   $ 600,000         $ 606,000      
The Alpha-1 Project, Inc. [Member]                    
Class of Warrant or Right [Line Items]                    
Fair value of common stock price per share     $ 4.33              
Contractual term of warrant     5 years              
Fair value of obligation risk free interest rate     1.07%              
Fair value of obligation expected volatility rate     72.00%              
Fair value of obligation expected dividend yield     0.00%              
Value of warrants     $ 26,000     $ 26,000        
The Alpha-1 Project, Inc. [Member] | Common Shares [Member]                    
Class of Warrant or Right [Line Items]                    
Warrant to purchase shares of common stock     10,000   10,000          
Exercise price     $ 4.33   $ 4.33          
Expiration period     5 years   5 years          
Series A and B Convertible Preferred Stock [Member]                    
Class of Warrant or Right [Line Items]                    
Gain (loss) on changes in fair value recorded in income statement           (800,000)        
Reclassification of fair value to permanent equity           $ 900,000        
LEI [Member]                    
Class of Warrant or Right [Line Items]                    
Warrant to purchase shares of common stock 40,000         40,000       25,000
Fair value of obligation to issue warrant $ 200,000         $ 8,000       $ 5,000
Exercise price $ 10.51               $ 2.75  
Fair value of common stock price per share $ 8.35         $ 2.90        
Warrant expiration date Oct. 15, 2020                  
Contractual term of warrant 5 years         5 years 7 months 6 days        
Fair value of obligation risk free interest rate 1.34%         1.20%        
Fair value of obligation expected volatility rate 75.00%         72.00%        
Fair value of obligation expected dividend yield 0.00%         0.00%        
LEI [Member] | Warrants [Member]                    
Class of Warrant or Right [Line Items]                    
Shares vested and exercisable               0    
Financial Services Firm [Member]                    
Class of Warrant or Right [Line Items]                    
Warrant to purchase shares of common stock       63,415            
Exercise price       $ 6.83            
Fair value of common stock price per share       $ 6.83            
Warrant expiration date       May 15, 2019            
Contractual term of warrant       5 years            
Financial Services Firm [Member] | Warrants [Member]                    
Class of Warrant or Right [Line Items]                    
Fair value of warrant liability       $ 300,000            
Fair value of obligation risk free interest rate       1.55%            
Fair value of obligation expected volatility rate       75.00%            
Fair value of obligation expected dividend yield       0.00%