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Note 2 - Liquidity (Details Textual) - USD ($)
1 Months Ended 9 Months Ended 12 Months Ended
Mar. 05, 2021
Mar. 31, 2019
Sep. 30, 2020
Dec. 31, 2019
Dec. 31, 2020
Retained Earnings (Accumulated Deficit), Ending Balance       $ (86,938,163) $ (102,148,817)
Working Capital         19,400,000
Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Ending Balance         22,400,000
Subsequent Event [Member] | Public Offering [Member]          
Stock Issued During Period, Shares, New Issues (in shares) 7,875,000        
Shares Issued, Price Per Share (in dollars per share) $ 8        
Proceeds from Issuance of Common Stock $ 63,000,000        
Sale of Stock, Option to Purchase Shares (in shares) 1,181,250        
JMP Securities, Inc [Member]          
Distribution Agreement, Aggregate Sales Price   $ 12,500,000      
Distribution Agreement, Amount Available for Sale         $ 10,200,000
Stock Issued During Period, Shares, New Issues (in shares)     0 398,709  
Proceeds from Issuance of Common Stock       $ 2,300,000