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Consolidated Statements of Stockholders' Equity - USD ($)
shares in Thousands, $ in Thousands
Total
Convertible Preferred Stock
Convertible Preferred Stock
Common Stock
Additional Paid-In Capital
Accumulated Deficit
Accumulated Other Comprehensive Income (Loss)
Public Offering
Public Offering
Common Stock
Public Offering
Additional Paid-In Capital
At-the-Market Offering
At-the-Market Offering
Common Stock
At-the-Market Offering
Additional Paid-In Capital
Balance at Dec. 31, 2019 $ 142,426       $ 428,485 $ (286,101) $ 42            
Balance, shares at Dec. 31, 2019       3,175                  
Issuance of common stock               $ 33,464   $ 33,464 $ 7,397   $ 7,397
Issuance of common stock, shares                 288     58  
Issuance of common stock pursuant to equity incentive plans 1,200       1,200                
Issuance of common stock pursuant to equity incentive plans, shares       13                  
Stock-based compensation expense 8,060       8,060                
Net loss (90,137)         (90,137)              
Unrealized loss on available-for-sale securities (39)           (39)            
Balance at Dec. 31, 2020 102,371       478,606 (376,238) 3            
Balance, shares at Dec. 31, 2020       3,534                  
Issuance of Series A convertible preferred stock, net of issuance costs of $173   $ 40,702                      
Issuance of Series A convertible preferred stock, net of issuance costs of $173, shares   1,000                      
Issuance of common stock                     10,661   10,661
Issuance of common stock, shares                       262  
Issuance of common stock pursuant to equity incentive plans 177       177                
Issuance of common stock pursuant to equity incentive plans, shares       61                  
Stock-based compensation expense 10,264       10,264                
Net loss (115,088)         (115,088)              
Unrealized loss on available-for-sale securities (3)           $ (3)            
Balance at Dec. 31, 2021 8,382       499,708 (491,326)              
Balance, shares at Dec. 31, 2021       3,857                  
Temporary equity, Balance at Dec. 31, 2021 $ 40,702 $ 40,702                      
Temporary equity, Balance, shares at Dec. 31, 2021 1,000 1,000                      
Reclassification of convertible preferred stock to stockholders' equity (Note 6) $ 40,702 $ (40,702) $ 40,702                    
Reclassification of convertible preferred stock to stockholders' equity (Note 6),shares   (1,000) 1,000                    
Deemed contribution from Series A preferred stock extinguishment (Note 6) 18,360   $ (18,360)     18,360              
Issuance of common stock               $ 5,775   $ 5,775 $ 1,137   $ 1,137
Issuance of common stock, shares                 926     62  
Issuance of common stock pursuant to equity incentive plans 16       16                
Issuance of common stock pursuant to equity incentive plans, shares       23                  
Stock-based compensation expense 4,030       4,030                
Net loss (39,650)         (39,650)              
Balance at Dec. 31, 2022 $ 20,392   $ 22,342   $ 510,666 $ (512,616)              
Balance, shares at Dec. 31, 2022     1,000 4,868                  
Temporary equity, Balance, shares at Dec. 31, 2022 0